RS 100329 HCl

• CAS: 215654-26-4
• Catalog Number: ACM215654264
• Category: Antagonists
• Molecular Weight: 462.90
• Molecular Formula: C20H26ClF3N4O3
• Description: RS 100329 is a subtype-selective α1A-adrenoceptor antagonist (pKi = 9.6 for human cloned α1A receptors). RS 100329 displays 126- and 50-fold selectivity over human α1B and α1D receptors respectively.
• Synonyms: RS-100329; RS 100329; RS100329; RS 100329 HCl; RS100329 HCl
• IUPAC Name: 5-methyl-3-(3-(4-(2-(2,2,2-trifluoroethoxy)phenyl)piperazin-1-yl)propyl)pyrimidine-2,4(1H,3H)-dione hydrochloride
• Canonical SMILES: CC1=CNC(N(C1=O)CCCN2CCN(C3=C(C=CC=C3)OCC(F)(F)F)CC2)=O.Cl
• InChI: InChI=1S/C20H25F3N4O3.ClH/c1-15-13-24-19(29)27(18(15)28)8-4-7-25-9-11-26(12-10-25)16-5-2-3-6-17(16)30-14-20(21,22)23;/h2-3,5-6,13H,4,7-12,14H2,1H3,(H,24,29);1H
• InChI Key: CWVABCXVOAVUJL-UHFFFAOYSA-N
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Shelf Life: >2 years if stored properly
• Storage: Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).
• Alternative CAS: 232953-52-5 (free base); 215654-26-4 (HCl)
• Drug Formulation: This drug may be formulated in DMSO
• Elemental Analysis: C, 51.89; H, 5.66; Cl, 7.66; F, 12.31; N, 12.10; O, 10.37
• Exact Mass: 462.1646
• HS Tariff Code: 2934.99.9001
• Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
• Stock Solution Storage: 0-4 °C for short term (days to weeks), or -20 °C for long term (months).