GLPG2938

• CAS: 2130996-00-6
• Catalog Number: ACM2130996006
• Category: Antagonists
• Molecular Weight: 503.41
• Molecular Formula: C20H19F6N7O2
• Description: GLPG2938 is an antagonists of sphingosine-​1-​phosphate (S1P) receptor for prophylaxis and​/or treatment of diseases including fibrotic, inflammatory, autoimmune, metabolic, cardiovascular, and​/or proliferative diseases. GLPG2938 displayed S1P inhibitory activity.with EC50 value of 9.5 nM (S1P2 antagonist EC50)​.
• Synonyms: MUN96006; MUN-96006; MUN 96006; GLPG2938; GLPG-2938; GLPG 2938
• IUPAC Name: 1-(2-ethoxy-6-(trifluoromethyl)pyridin-4-yl)-3-((5-methyl-6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)pyridazin-3-yl)methyl)urea
• Canonical SMILES: O=C(NCC1=NN=C(C2=CN(C)N=C2C(F)(F)F)C(C)=C1)NC3=CC(OCC)=NC(C(F)(F)F)=C3
• InChI: InChI=1S/C20H19F6N7O2/c1-4-35-15-7-11(6-14(29-15)19(21,22)23)28-18(34)27-8-12-5-10(2)16(31-30-12)13-9-33(3)32-17(13)20(24,25)26/h5-7,9H,4,8H2,1-3H3,(H2,27,28,29,34)
• InChI Key: MGJMUVKYINFAQC-UHFFFAOYSA-N
• Solubility: To be determined
• Appearance: Solid powder
• Shelf Life: >2 years if stored properly
• Storage: Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).
• Biological Target: GLPG2938 is a potent and selective S1P2 antagonist.
• Drug Formulation: To be determined
• Elemental Analysis: C, 47.72; H, 3.80; F, 22.64; N, 19.48; O, 6.36
• Exact Mass: 503.1504
• HS Tariff Code: 2934.99.9001
• In Vitro Activity: TBD
• In Vivo Activity: TBD
• Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
• Stock Solution Storage: 0-4 °C for short term (days to weeks), or -20 °C for long term (months).