Pterostilbene

• CAS: 537-42-8
• Catalog Number: ACM537428
• Category: Material of Cosmetics
• Molecular Weight: 256.3
• Molecular Formula: C16H16O3
• Description: Pterostilbene is a stilbenoid chemically related to resveratrol. In plants, it serves a defensive phytoalexin role.
• Synonyms: 3,5-Dimethoxy-4'-hydroxystilbene
• IUPAC Name: 4-[(E)-2-(3,5-Dimethoxyphenyl)ethenyl]phenol
• Canonical SMILES: COC1=CC(=CC(=C1)C=CC2=CC=C(C=C2)O)OC
• InChI: InChI=1S/C16H16O3/c1-18-15-9-13(10-16(11-15)19-2)4-3-12-5-7-14(17)8-6-12/h3-11,17H,1-2H3/b4-3+
• InChI Key: VLEUZFDZJKSGMX-ONEGZZNKSA-N
• Boiling Point: 420.4±35.0 °C
• Melting Point: 89-92 °C
• Flash Point: 208.1ºC
• Density: 1.169±0.06 g/cm³
• Appearance: Off-white crystalline powder
• Effective Constituent: Pterostilbene
• Exact Mass: 256.109944368
• Hazard Codes: Xi
• HS Code: 2909500000
• Isomeric SMILES: COC1=CC(=CC(=C1)/C=C/C2=CC=C(C=C2)O)OC
• LogP: 3.57980
• MDL Number: MFCD00238710
• Monoisotopic Mass: 256.109944368
• Physical State: Solid
• PSA: 38.69
• Refractive Index: 1.639
• RIDADR: UN 3077
• Storage Conditions: 2-8 °C
• Topological Polar Surface Area: 38.7 Ų
• Vapor Pressure: 1.15E-07mmHg at 25°C

Custom Q&A

What is the molecular formula of Pterostilbene?

The molecular formula of Pterostilbene is C16H16O3.

What is the molecular weight of Pterostilbene?

The molecular weight of Pterostilbene is 256.30 g/mol.

What are the synonyms of Pterostilbene?

The synonyms of Pterostilbene are trans-pterostilbene, 4-(3,5-Dimethoxystyryl)phenol, and (E)-4-(3,5-dimethoxystyryl)phenol.

Is Pterostilbene a natural product?

Yes, Pterostilbene is a natural product found in Vitis rupestris, Pterocarpus marsupium, and other organisms.

What are the potential benefits of Pterostilbene?

Pterostilbene has potential antioxidant, anti-inflammatory, pro-apoptotic, antineoplastic, and cytoprotective activities.

How does Pterostilbene exert its antioxidant activity?

Pterostilbene exerts its antioxidant activity by scavenging reactive oxygen species (ROS) and preventing oxidative stress and ROS-induced cell damage.

Does Pterostilbene activate any specific pathway?

Pterostilbene may activate the nuclear factor erythroid 2-related factor 2 (Nrf2)-mediated pathway and increase the expression of various antioxidant enzymes.

Does Pterostilbene have any anti-inflammatory effects?

Yes, Pterostilbene can reduce the expression of various inflammatory mediators and inhibit inflammation.

How does Pterostilbene affect signaling pathways involved in cancer?

Pterostilbene can inhibit or prevent the activation of signaling pathways involved in carcinogenesis and increase the expression of tumor suppressor genes while decreasing expression of certain tumor promoting genes.

Does Pterostilbene induce apoptosis in tumor cells?

Yes, Pterostilbene directly induces apoptosis in tumor cells.

Synthetic Use

Upstream Synthesis Route 1

• 441351-31-1

• 537-42-8

Reference: [1]Bioorganic and Medicinal Chemistry Letters,2006,vol. 16,p. 5767 - 5772
[2]Journal of Medicinal Chemistry,2002,vol. 45,p. 2534 - 2542
[3]Journal of Medicinal Chemistry,2003,vol. 46,p. 3546 - 3554

Upstream Synthesis Route 2

• 848487-76-3

• 537-42-8

Reference: [1]Journal of Medicinal Chemistry,2005,vol. 48,p. 1292 - 1295
[2]Journal of Medicinal Chemistry,2012,vol. 55,p. 883 - 892
[3]Medicinal Chemistry Research,2016,vol. 25,p. 627 - 643

Downstream Synthesis Route 1

• 537-42-8
• 74-88-4

• 22255-22-7

Reference: [1]Bioorganic and Medicinal Chemistry Letters,2006,vol. 16,p. 5767 - 5772
[2]Patent: WO2008/70872,2008,A1 .Location in patent: Page/Page column 26-27

* For details of the synthesis route, please refer to the original source to ensure accuracy.