Structure

Picroside Ii

CAS
39012-20-9
Catalog Number
ACM39012209
Category
Inhibitors
Molecular Weight
512.46
Molecular Formula
C23H28O13

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Specification

Description
Picroside II, an iridoid compound extracted from Picrorhiza, exhibits anti-inflammatory and anti-apoptotic activities.picroside II alleviates the inflammatory response in sepsis and enhances immune function by inhibiting the activation of NLRP3 inflammasome and NF-κB pathways.Picroside II is an antioxidant, exhibits a significant neuroprotective effect through reducing ROS production and protects the blood-brain barrier (BBB) after cerebral ischemia-reperfusion (CI/R) injury. Picroside II has antioxidant, anti-inflammatory, immune regulatory, anti-virus and other pharmacological activities.
Canonical SMILES
O[C@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)[C@@H]1O[C@H]2[C@@]3([H])[C@@]([C@H](OC(C4=CC=C(O)C(OC)=C4)=O)[C@@]5([H])[C@]3(CO)O5)([H])C=CO2
Appearance
Solid
Storage
4°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light).
Shipping
Can be shipped at room temperature, where not in use may vary.
Source
PlantsScrophulariaceaePicrorhiza scrophulariiflora Pennell
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