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Structure

Cynaropicrin

CAS
35730-78-0
Catalog Number
ACM35730780
Category
Inhibitors
Molecular Weight
346.37
Molecular Formula
C19H22O6
MSDS COA Spec Sheet

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Description
Cynaropicrin is a sesquiterpene lactone which can inhibit tumor necrosis factor (TNF-α) release with IC50s of 8.24 and 3.18 μM for murine and human macrophage cells, respectively. Cynaropicrin also inhibits the increase of cartilage degradation factor (MMP13) and suppresses NF-κBsignaling.
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