Noscapine hydrochloride

• CAS: 912-60-7
• Catalog Number: ACM912607
• Category: Other Products
• Molecular Weight: 449.9
• Molecular Formula: C₂₂H₂₃NO₇.HCl
• Synonyms: 1-alpha-Narcotinehydrochloride
• IUPAC Name: (3S)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-2-benzofuran-1-one hydrochloride
• Canonical SMILES: CN1CCC2=CC3=C(C(=C2C1C4C5=C(C(=C(C=C5)OC)OC)C(=O)O4)OC)OCO3.O.Cl
• InChI: InChI=1S/C22H23NO7.ClH/c1-23-8-7-11-9-14-20(29-10-28-14)21(27-4)15(11)17(23)18-12-5-6-13(25-2)19(26-3)16(12)22(24)30-18;/h5-6,9,17-18H,7-8,10H2,1-4H3;1H/t17-,18+;/m1./s1
• InChI Key: MFLVZFXCSKVCSH-URBRKQAFSA-N
• Boiling Point: 565.3ºC at 760mmHg
• Melting Point: 221-223 °C
• Flash Point: 295.7ºC
• Density: 1.332g/cm³
• Complexity: 647
• Covalently-Bonded Unit Count: 2
• Defined Atom Stereocenter Count: 2
• EC Number: 213-014-9
• Exact Mass: 449.1241298
• Hazard Statements: Xi:Irritant
• H-Bond Acceptor: 8
• H-Bond Donor: 1
• Heavy Atom Count: 31
• Hydrogen Bond Acceptor Count: 8
• Hydrogen Bond Donor Count: 1
• Isomeric SMILES: CN1CCC2=CC3=C(C(=C2[C@@H]1[C@@H]4C5=C(C(=C(C=C5)OC)OC)C(=O)O4)OC)OCO3.Cl
• Monoisotopic Mass: 449.1241298
• Packing Group: III
• Physical State: Solid
• Rotatable Bond Count: 4
• Safety Description: S36
• Topological Polar Surface Area: 75.7 Ų

Custom Q&A

What is the chemical formula of Noscapine hydrochloride?

The chemical formula of Noscapine hydrochloride is C22H24ClNO7.

What is the melting point of Noscapine hydrochloride?

The melting point of Noscapine hydrochloride is 221-223°C.

In what form is Noscapine hydrochloride stored?

Noscapine hydrochloride is stored in a temperature range of 2-8°C.

What is the solubility of Noscapine hydrochloride?

Noscapine hydrochloride is freely soluble in water and in ethanol (96 per cent).

What are the hazard codes associated with Noscapine hydrochloride?

The hazard codes associated with Noscapine hydrochloride are Xn and Xi.

What is the primary usage of Noscapine hydrochloride?

Noscapine hydrochloride is used as an anti-tussive agent.

What type of inhibitor is Noscapine hydrochloride?

Noscapine hydrochloride is a bradykinin B and tubulin inhibitor.

What is the safety profile of Noscapine hydrochloride?

Noscapine hydrochloride is moderately toxic by ingestion and subcutaneous routes.

What are the safety statements associated with Noscapine hydrochloride?

The safety statements associated with Noscapine hydrochloride are 36.

What are the biological activities of Noscapine hydrochloride?

Noscapine hydrochloride binds to tubulin, arrests cells in mitosis, induces apoptosis, and acts as an antagonist at bradykinin receptors. It is also an anti-viral agent.