Specification
Description
NKY80 is a inhibitor of adenylyl cyclase (AC). NKY80 exhibits greater affinity for AC5 over AC3 and AC2 (IC50 values are 8.3 μM, 132 μM and 1.7 mM respectively).
Synonyms
NKY80; NKY 80; NKY-80
IUPAC Name
2-amino-7-(furan-2-yl)-5,6,7,8-tetrahydroquinazolin-5-one
Canonical SMILES
O=C1C2=CN=C(N)N=C2CC(C3=CC=CO3)C1
InChI
InChI=1S/C12H11N3O2/c13-12-14-6-8-9(15-12)4-7(5-10(8)16)11-2-1-3-17-11/h1-3,6-7H,4-5H2,(H2,13,14,15)
InChI Key
SOJUSNIBPPMLCC-UHFFFAOYSA-N
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Storage
Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).
Drug Formulation
This drug may be formulated in DMSO
Elemental Analysis
C, 62.87; H, 4.84; N, 18.33; O, 13.96
HS Tariff Code
2934.99.9001
Shipping
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Stock Solution Storage
0-4 °C for short term (days to weeks), or -20 °C for long term (months).