Structure

Merbarone

CAS
97534-21-9
Catalog Number
ACM97534219
Category
Inhibitors
Molecular Weight
263.27
Molecular Formula
C11H9N3O3S

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Specification

Description
Merbarone (NSC 336628) is an orally active inhibitor of topoisomerase II. Merbarone acts primarily by blocking topoisomerase II-mediated DNA cleavage without stabilizing topo II-DNA covalent complexes. Merbarone is an anticancer agent.
Canonical SMILES
O=C(C(C(N1)=O)C(NC1=S)=O)NC2=CC=CC=C2
Appearance
Solid
Storage
Powder-20°C, 3 years; 4°C, 2 years; In solvent-80°C, 6 months; -20°C, 1 month.
Shipping
Can be shipped at room temperature, where not in use may vary.
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