k-252a

• CAS: 99533-80-9
• Catalog Number: ACM99533809
• Category: Inhibitors
• Molecular Weight: 467.47
• Molecular Formula: C₂₇H₂₁N₃O₅
• Description: K-252a, a staurosporine analog, inhibits protein kinase, with IC50 values of 470 nM, 140 nM, 270 nM, and 1.7 nM for PKC, PKA, Ca2+/calmodulin-dependent kinase type II, and phosphorylase kinase, respectively. K-252a is a potent inhibitor (IC50 of 3 nM) of the tyrosine protein kinase (TRK) activity of the NGF receptor gp140trk, the product of the trk protooncogene.