MDMO-PPV

• CAS: 177716-59-5
• Catalog Number: ACM177716595
• Category: Flexible Printed Electronics
• Molecular Weight: Mn ~120,000
• Molecular Formula: C21H23ClFNO2
• Description: MDMO-PPV is a dialkoxy substituted poly(p-phenylenevinylene) (PPV) based conjugating polymer which has long side chains that form flexible films for organic electronics. It is a piezoresistant polymer with HOMO and LUMO orbital positions at 5.4 and 3.4 eV, respectively. MDMO-PPV forms an active layer that can be used in photoconductive and electroluminescent applications
• Synonyms: Poly[2-methoxy-5-(3',7'-dimethyloctyloxy)-1,4-phenylenevinylene]
• IUPAC Name: 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one
• Canonical SMILES: COc1ccc(OCCC(C)CCCC(C)C)cc1C=C
• InChI: InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2
• InChI Key: LNEPOXFFQSENCJ-UHFFFAOYSA-N
• Melting Point: 216 ℃
• Flash Point: Not applicable
• Solubility: soluble in Toluene, Xylene, THF, Chloroform, Chlorobenzene, Cyclohexanone
• Application: MDMO-PPV can also be used in the fabrication of bulk heterojunction solar cells(BHJ).
• Storage: room temp
• Color/Form: Crystals;WHITE TO FAINTLY YELLOWISH, AMORPHOUS OR MICRO-CRYSTALLINE POWDER
• Complexity: 451
• Covalently-Bonded Unit Count: 1
• EC Number: 200-155-6;612-377-4
• Exact Mass: 375.140135g/mol
• Form: ITO/PEDOT:PSS/MDMO-PPV/PC61BM/Al[13]• Short-circuit current density (Jsc): 0.96 mA/cm² • Open-circuit voltage (Voc): 0.78 V• Fill Factor (FF): 0.5• Power Conversion Efficiency (PCE): 0.5 %
• Formal Charge: 0
• Hazard Statements: H319
• H-Bond Acceptor: 4
• H-Bond Donor: 1
• Heavy Atom Count: 26
• LogP: 4.3 (LogP);log Kow = 4.30;4
• MDL Number: MFCD03458070
• Monoisotopic Mass: 375.140135g/mol
• NSC Number: 757054;615296;170973
• Other Experimental: Crystals; mp 226-227.5 °C; sol in water at 300X10+1 mg/L /Hydrochloride/;Henry's Law constant = 2.3X10-14 atm-cu m/mol @ 25 °C /Estimated/;Hydroxyl radical reaction rate constant = 1.2X10-10 cu cm/molec-sec @ 25 °C /Estimated/
• Packaging: 1 g in glass bottle
• Precautionary Statements: P305+P351+P338
• Quality Level: 100
• Rotatable Bond Count: 6
• Signal Word: Warning
• UNII: J6292F8L3D
• Vapor Pressure: 4.8X10-11 mm Hg @ 25 °C /Estimated/
• XLogP3: 3.2

Custom Q&A

What is the molecular formula of haloperidol?

The molecular formula of haloperidol is C21H23ClFNO2.

What is the molecular weight of haloperidol?

The molecular weight of haloperidol is 375.9 g/mol.

What is the role of haloperidol as?

Haloperidol has a role as a serotonergic antagonist, a first generation antipsychotic, a dopaminergic antagonist, an antidyskinesia agent, and an antiemetic.

What receptors does haloperidol primarily antagonize in the brain?

Haloperidol primarily antagonizes the dopamine receptor, mainly D2.

What are some of the psychotic disorders for which haloperidol is indicated for treatment?

Haloperidol is indicated for the treatment of schizophrenia, acute psychosis, Tourette syndrome, and other severe behavioral states.

What is the benefit of using first-generation antipsychotics like haloperidol for managing "positive" symptoms of schizophrenia?

First-generation antipsychotics like haloperidol are highly effective for managing symptoms such as hallucinations, aggression, disorganized speech, and psychomotor agitation.

What are some of the movement disorders induced by dopamine blockade that can be caused by haloperidol?

Movement disorders induced by dopamine blockade that can be caused by haloperidol include drug-induced parkinsonism, akathisia, dystonia, and tardive dyskinesia.

How does haloperidol compare to lower-potency first-generation antipsychotics in terms of side effects?

Haloperidol typically demonstrates the least amount of side effects within its class, but has a stronger disposition for causing extrapyramidal symptoms.

How is haloperidol's metabolism affected by genetically determined polymorphic CYP2D6 activity?

In vivo pharmacogenetic studies suggest that the metabolism of haloperidol may be modulated by genetically determined polymorphic CYP2D6 activity.

What newer generation antipsychotics have largely replaced first-generation antipsychotics like haloperidol?

Second- and third-generation antipsychotics such as risperidone, olanzapine, quetiapine, aripiprazole, clozapine, and lurasidone have largely replaced first-generation antipsychotics like haloperidol.