Licarin A

• CAS: 51020-86-1
• Catalog Number: ACM51020861
• Category: Inhibitors
• Molecular Weight: 326.39
• Molecular Formula: C20H22O4
• Description: Licarin A ((+)-Licarin A), a neolignan, significantly and dose-dependently reduces TNF-α production (IC50=12.6 μM) in dinitrophenyl-human serum albumin (DNP-HSA)-stimulated RBL-2H3 cells. Anti-allergic effects. Licarin A reduces TNF-α and PGD2 production, and COX-2 expression.
• Canonical SMILES: OC1=CC=C([C@@H]2OC3=C(OC)C=C(/C=C/C)C=C3[C@H]2C)C=C1OC
• Appearance: Solid
• Storage: 4°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light).
• Shipping: Can be shipped at room temperature, where not in use may vary.
• Source: PlantsSaururaceaeSaururus chinensis (Lour.) Baill.

Synthetic Use

Upstream Synthesis Route 1

• 5932-68-3

• 97-53-0
• 51020-86-1
• 458-35-5
• 121-33-5

Reference: [1] Biocatalysis and Biotransformation, 2011, vol. 29, # 4, p. 147 - 150