l189

CAS
64232-83-3
Catalog Number
ACM64232833
Category
Inhibitors
Molecular Weight
C11H10N4OS
Molecular Formula
C11H10N4OS?xH2O

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Specification

Description
L189 is a DNA ligase inhibitor. L189 has inhibition effect for DNA Ligase I, III and IV with IC50 values of 5 μM, 9 μM and 5 μM, respectively. L189 has no cytotoxicity and individually increase cell death. L189 can be used for the research of cancer.
Canonical SMILES
OC1=NC(S)=NC(N)=C1/N=C/C2=CC=CC=C2
Appearance
Solid
Storage
Powder-20°C, 3 years; 4°C, 2 years; In solvent-80°C, 6 months; -20°C, 1 month.
Shipping
Can be shipped at room temperature, where not in use may vary.
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