Mebio

• CAS: 667463-95-8
• Catalog Number: ACM667463958
• Category: Inhibitors
• Molecular Weight: 370.206 g/mol
• Molecular Formula: C17H12BrN3O2
• Description: MeBIO is a potent AhR (aryl hydrocarbon receptor) agonist, with IC50 of 44 μM (GSK-3) and 55 μM (CDK1/cyclin B), respectively. MeBIO is inactive on GSK-3β.
• Synonyms: MeBIO; Me-BIO; Me BIO
• IUPAC Name: (2Z,3E)-6-Bromo-1-methylindirubin-3-oxime
• Canonical SMILES: O=C(/C1=C2NC3=C(C\2=N/O)C=CC=C3)N(C)C4=C1C=CC(Br)=C4
• InChI: InChI=1S/C17H12BrN3O2/c1-21-13-8-9(18)6-7-11(13)14(17(21)22)16-15(20-23)10-4-2-3-5-12(10)19-16/h2-8,19,23H,1H3/b16-14-,20-15+
• InChI Key: JUKQKURGZYNHFN-NVVUQHMZSA-N
• Appearance: Solid powder
• Shelf Life: >3 years if stored properly
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• Drug Formulation: This drug may be formulated in DMSO
• Elemental Analysis: C, 55.15; H, 3.27; Br, 21.58; N, 11.35; O, 8.64
• Exact Mass: 369.0113
• H-Bond Acceptor: 4
• H-Bond Donor: 2
• HS Tariff Code: 2934.99.03.00
• Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
• Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).