L-Leucinefrom non-animal source

CAS

61-90-5

Catalog Number

ACM61905-3

Category

Amino Acids

Molecular Weight

131.17

Molecular Formula

(CH3)2CHCH2CH(NH2)CO2H

MSDS COA Spec Sheet

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Specification

Description

Leucine is a non-glucogenic, and essential amino acid. It is a branched-chain amino acid that is a structural component of proteins.

Synonyms

(S)-Leucine, (S)-2-Amino-4-methylpentanoic acid

Canonical SMILES

CC(C)C[C@H](N)C(O)=O

InChI

1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1

InChI Key

ROHFNLRQFUQHCH-YFKPBYRVSA-N

Melting Point

>300 ℃(lit.)

Solubility

1 M HCl: 50 mg/mL

Application

L-Leucine has been used:
as a hypertrophic agent to monitor its effects on myotubes.
as a component of PMG media for culturing yeast.
in myotube protein synthesis analysis in skeletal muscle cells.
to study its effects on hepatic lipid metabolism.

Assay

98.5-101.0%

Beilstein

1721722

Biochem Physiol Actions

Leucine plays a role in intracellular signaling, gene transcription, and translation. It promotes the synthesis of protein by activating the mammalian target of the rapamycin (mTOR) signaling pathway in placental cells, skeletal muscles, and adipose tissue. Leucine inhibits protein degradation and promotes mitochondrial biogenesis, glucose metabolism, and fatty acid oxidation to provide energy for protein synthesis.

Biological Source

non-animal source

Color

white

EC Number

200-522-0

Form

powder

Impurity Content

endotoxin, tested

MDL Number

MFCD00002617