L-Leucine, reagent grade, ≥98% (HPLC)

• CAS: 61-90-5
• Catalog Number: ACM61905-2
• Category: Amino Acids
• Molecular Weight: 131.17
• Molecular Formula: (CH3)2CHCH2CH(NH2)CO2H
• Synonyms: (S)-2-Amino-4-methylpentanoic acid
• Canonical SMILES: CC(C)C[C@H](N)C(O)=O
• InChI: 1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1
• InChI Key: ROHFNLRQFUQHCH-YFKPBYRVSA-N
• Melting Point: >300 ℃(lit.)
• Application: L-Leucine has been used as an agonist of mechanistic target of rapamycin (mTOR) to determine whether AMPK/mTOR pathway is involved in berberine-mediated autophagy in J774A.1 cells. It has also been used for the selection of transformed cells.
• Assay: ≥98% (HPLC)
• Beilstein: 1721722
• Biochem Physiol Actions: Leucine is a non-glucogenic, essential amino acid. It is a branched-chain amino acid that is a structural component of proteins. Leucine positively influences insulin release to eliminate toxic sugars out of the blood. The degradation of leucine leads to the formation of ketone bodies.
• Color: white to off-white
• EC Number: 200-522-0
• Form: powder
• Grade: reagent grade
• Impurity Content: isoleucine and methionine, essentially free
• MDL Number: MFCD00002617
• NACRES: NA.26
• PubChem ID: 24896488
• Quality Level: 200
• Storage Temperature: 2-8℃
• Technique: ligand binding assay: suitable