Hydroxychloroquine sulfate

• CAS: 747-36-4
• Catalog Number: ACM747364-1
• Category: Inhibitors
• Molecular Weight: 433.95
• Molecular Formula: C18H28ClN3O5S
• Description: Hydroxychloroquine sulfate (HCQ sulfate) is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine sulfate is efficiently inhibits SARS-CoV-2 infection in vitro.
• Synonyms: 7-Chloro-4-[4-(N-ethyl-N-b-hydroxyethylamino)-1-methylbutylamino]quinoline sulfate
• IUPAC Name: 2-[4-[(7-chloroquinolin-4-yl)amino]pentyl-ethylamino]ethanol;sulfuric acid
• Canonical SMILES: CCN(CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl)CCO.OS(=O)(=O)O
• InChI: InChI=1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4)
• InChI Key: JCBIVZZPXRZKTI-UHFFFAOYSA-N
• Appearance: White to off-white solid

Synthetic Use

Downstream Synthesis Route 1

• 556-52-5
• 747-36-4

• 877128-78-4

Reference: [1]Current Patent Assignee: Kosak, Kenneth M. - US2007/60499, 2007, A1
Location in patent: Page/Page column 26

* For details of the synthesis route, please refer to the original source to ensure accuracy.