Structure

Cytochalasin e

CAS
36011-19-5
Catalog Number
ACM36011195
Category
Inhibitors
Molecular Weight
495.56
Molecular Formula
C28H33NO7

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Specification

Description
Cytochalasin E, an epoxide containing Aspergillus-derived fungal metabolite, inhibits angiogenesis and tumor growth. Cytochalasin E is a potent actin depolymerization agent, and it binds and caps the barbed end of actin filaments to prevent actin elongation.
Synonyms
(7s,13e,16s,18r,19e)-18-dimethyl-10-phenyl;21,23-dioxa(13)cytochalasa-13,19-diene-1,17,22-trione,6,7-epoxy-18-hydroxy-16,;6,7-epoxy-10-phenyl-5,6,16,18-tetramethyl-21,23-dioxa-[13]cytochalas-13,19-die;CYTOCHALASIN 3;CYTOCHALASIN E;CYTOCHALASIN E, ASPERGI
IUPAC Name
CYTOCHALASIN E
Canonical SMILES
CC1CC=CC2C3C(O3)(C(C4C2(C(=O)NC4CC5=CC=CC=C5)OC(=O)OC=CC(C1=O)(C)O)C)C
InChI Key
LAJXCUNOQSHRJO-ZYGJITOWSA-N
Boiling Point
705.1ºC at 760 mmHg
Melting Point
206ºC
Flash Point
380.2ºC
Density
1.3 g/cm³
Appearance
white powder
Storage
Powder-20°C, 3 years; In solvent-80°C. 6 months; -20°C, 1 month.
EC Number
252-835-7
Exact Mass
495.22600
Hazard Statements
T+,T
Shipping
Can be shipped at room temperature, where not in use may vary.
Source
The fungus R. necatrix
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