Herboxidiene

• CAS: 142861-00-5
• Catalog Number: ACM142861005
• Category: Inhibitors
• Molecular Weight: 438.60
• Molecular Formula: C25H42O6
• Description: Herboxidiene (GEX1A) is a potent phytotoxic polyketide from Streptomyces sp. A7847 with a diverse range of activities, including herbicidal, anti-cholesterol, anti-tumor effects. Herboxidiene inhibits the pre-mRNA splicing process by binding to spliceosome-associated protein (SAP) 155, a subunit of SF3b, in the splicesome.
• Synonyms: Herboxidiene
• Canonical SMILES: C[C@H]([C@H]([C@H](O)C)OC)[C@@]1([H])O[C@]1(C)C[C@@H](/C=C/C=C(C)/[C@H]2O[C@@H](CC(O)=O)CC[C@@H]2C)C
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Shipping: Can be shipped at room temperature, where not in use may vary.
• Source: Streptomyces chromofuscus A7847

Custom Q&A

What is the molecular formula of Herboxidiene?

The molecular formula of Herboxidiene is C25H42O6.

What is the molecular weight of Herboxidiene?

The molecular weight of Herboxidiene is 438.6 g/mol.

What is the CAS number of Herboxidiene?

The CAS number of Herboxidiene is 142861-00-5.

What is the IUPAC name of Herboxidiene?

The IUPAC name of Herboxidiene is 2-[(2R,5S,6S)-6-[(2E,4E,6S)-7-[(2R,3R)-3-[(2R,3R,4R)-4-hydroxy-3-methoxypentan-2-yl]-2-methyloxiran-2-yl]-6-methylhepta-2,4-dien-2-yl]-5-methyloxan-2-yl]acetic acid.

What is the InChIKey of Herboxidiene?

The InChIKey of Herboxidiene is ISZXEMUWHQLLTC-LSIVYLFASA-N.

What is the XLogP3-AA value of Herboxidiene?

The XLogP3-AA value of Herboxidiene is 4.1.

How many hydrogen bond donor counts does Herboxidiene have?

Herboxidiene has 2 hydrogen bond donor counts.

How many hydrogen bond acceptor counts does Herboxidiene have?

Herboxidiene has 6 hydrogen bond acceptor counts.

How many rotatable bond counts does Herboxidiene have?

Herboxidiene has 11 rotatable bond counts.

What is the topological polar surface area of Herboxidiene?

The topological polar surface area of Herboxidiene is 88.5 ?2.