Fumagillin

• CAS: 23110-15-8
• Catalog Number: ACM23110158
• Category: Inhibitors
• Molecular Weight: 458.55 g/mol
• Molecular Formula: C26H34O7
• Description: Fumagillin(NSC9168) is an antimicrobial compound first isolated in 1949 from the fungus Aspergillus fumigatu. Fumagillin can inhibits HIV-1 infection through the inhibition of HIV-1 viral protein R (Vpr) activity.
• Synonyms: NSC9168; NSC 9168; NSC-9168; Fumidil B; Fumagillin, trade name: Fumagilina; Fugillin; Fumidil.
• IUPAC Name: (2E,4E,6E,8E)-10-(((3R,4S,5S,6R)-5-methoxy-4-((2R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl)-1-oxaspiro[2.5]octan-6-yl)oxy)-10-oxodeca-2,4,6,8-tetraenoic acid
• Canonical SMILES: O=C(O)/C=C/C=C/C=C/C=C/C(O[C@H](CC1)[C@@H](OC)[C@H]([C@@]2(C)OC2C/C=C(C)\C)[C@]31CO3)=O
• InChI: InChI=1S/C26H34O7/c1-18(2)13-14-20-25(3,33-20)24-23(30-4)19(15-16-26(24)17-31-26)32-22(29)12-10-8-6-5-7-9-11-21(27)28/h5-13,19-20,23-24H,14-17H2,1-4H3,(H,27,28)/b7-5+,8-6+,11-9+,12-10+/t19-,20?,23-,24-,25+,26+/m1/s1
• InChI Key: NGGMYCMLYOUNGM-IJIYPQOHSA-N
• Melting Point: 194-195°C
• Appearance: Solid powder
• Shelf Life: >2 years if stored properly
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• Drug Formulation: This drug may be formulated in DMSO
• Elemental Analysis: C, 68.10; H, 7.47; O, 24.42
• Exact Mass: 458.23045
• Hazard Statements: Xn,F
• HS Tariff Code: 2934.99.9001
• Safety Description: 36-36/37-16
• Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
• Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
• Supplemental Hazard Statements: H225-H302-H312-H319-H332
• Symbol: GHS07,GHS02

Custom Q&A

What is the molecular formula of fumagillin?

The molecular formula of fumagillin is C26H34O7.

What is the molecular weight of fumagillin?

The molecular weight of fumagillin is 458.5 g/mol.

What are the synonyms for fumagillin?

The synonyms for fumagillin include "fumagillin, 23110-15-8, Fugillin, Fumidil, Fumagillinum," and more.

What is the IUPAC name of fumagillin?

The IUPAC name of fumagillin is (2E,4E,6E,8E)-10-[[(3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-yl]oxy]-10-oxodeca-2,4,6,8-tetraenoic acid.

What is the InChI of fumagillin?

The InChI of fumagillin is InChI=1S/C26H34O7/c1-18(2)13-14-20-25(3,33-20)24-23(30-4)19(15-16-26(24)17-31-26)32-22(29)12-10-8-6-5-7-9-11-21(27)28/h5-13,19-20,23-24H,14-17H2,1-4H3,(H,27,28)/b7-5+,8-6+,11-9+,12-10+/t19-,20-,23-,24-,25+,26+/m1/s1.

What is the PubChem CID of fumagillin?

The PubChem CID of fumagillin is 6917655.

Is fumagillin an antibacterial drug?

Yes, fumagillin is an antibacterial drug.

Where is fumagillin originally isolated from?

Fumagillin is originally isolated from the fungus Aspergillus fumigatus.

What role does fumagillin have as an angiogenesis inhibitor?

Fumagillin has a role as an angiogenesis inhibitor, which means it inhibits the formation of new blood vessels.

What is the ChEBI ID of fumagillin?

The ChEBI ID of fumagillin is CHEBI:32838.