Fmoc-Phe-OH

• CAS: 35661-40-6
• Catalog Number: ACM35661406
• Category: Amino Acids
• Molecular Weight: 387.43
• Molecular Formula: C24H21NO4
• Description: High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities.; Standard building block for introduction of phenylalanine amino-acid residues by Fmoc SPPS.
• Synonyms: Fmoc-Phe-OH, N-α-Fmoc-L-phenylalanine
• InChI: 1S/C24H21NO4/c26-23(27)22(14-16-8-2-1-3-9-16)25-24(28)29-15-21-19-12-6-4-10-17(19)18-11-5-7-13-20(18)21/h1-13,21-22H,14-15H2,(H,25,28)(H,26,27)
• InChI Key: SJVFAHZPLIXNDH-UHFFFAOYSA-N
• Melting Point: 180-188℃
• Application: Peptide synthesis.
• Assay: ≥98% (TLC); ≥98.0% (acidimetric); ≥99.0% (HPLC)
• Form: powder
• Functional Group: Fmoc
• MDL Number: MFCD00037128
• Quality Level: 400
• Reaction Suitability: reaction type: Fmoc solid-phase peptide synthesis
• Storage Temperature: 2-30℃
• Type: Unlabeled Standard Amino Acids, Phenylalanine (Phe)

Synthetic Use

Downstream Synthesis Route 1

• 35661-40-6

• 5241-58-7

Reference: [1] Journal of the Chemical Society, Chemical Communications, 1988, # 5, p. 382 - 384
[2] Journal of Medicinal Chemistry, 2013, vol. 56, # 7, p. 2841 - 2849

Downstream Synthesis Route 2

• 35661-40-6

• 129397-83-7

Reference: [1] Tetrahedron Letters, 2012, vol. 53, # 38, p. 5059 - 5063

Downstream Synthesis Route 3

• 35661-40-6
• 244633-31-6

• 86060-92-6

Reference: [1] Tetrahedron Letters, 1999, vol. 40, # 32, p. 5939 - 5942

Downstream Synthesis Route 4

• 20866-48-2
• 35661-40-6
• 71989-14-5
• 125238-99-5

• 110116-75-1

Reference: [1]Journal of Medicinal Chemistry,1987,vol. 30,p. 2094 - 2099

* For details of the synthesis route, please refer to the original source to ensure accuracy.