Fmoc-Nle-OH

• CAS: 77284-32-3
• Catalog Number: ACM77284323
• Category: Amino Acids
• Molecular Weight: 353.41
• Molecular Formula: C21H23NO4
• Description: Standard building block for introduction of norleucine amino-acid residues by Fmoc SPPS.
• Synonyms: Fmoc-Nle-OH, N-α-Fmoc-L-norleucine
• InChI: 1S/C21H23NO4/c1-2-3-12-19(20(23)24)22-21(25)26-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,2-3,12-13H2,1H3,(H,22,25)(H,23,24)/p-1/t19-/m1/s1
• InChI Key: VCFCFPNRQDANPN-LJQANCHMSA-M
• Melting Point: 135-145℃
• Application: Peptide synthesis.
• Assay: ≥96.0% (acidimetric); ≥98% (TLC); ≥98.0% (HPLC)
• Form: powder
• Functional Group: Fmoc
• MDL Number: MFCD00037537
• Quality Level: 200
• Reaction Suitability: reaction type: Fmoc solid-phase peptide synthesis
• Storage Temperature: 2-30℃
• Type: Unusual Amino Acids, Analogs of Alanine, Glycine, Valine, and Leucine

Synthetic Use

Upstream Synthesis Route 1

• 947154-63-4

• 77284-32-3

Reference: [1] Journal of Peptide Science, 2013, vol. 19, # 8, p. 470 - 476
[2] Patent: WO2014/5197, 2014, A1, . Location in patent: Page/Page column 48-49