Fmoc-N-Me-Phe-OH

• CAS: 77128-73-5
• Catalog Number: ACM77128735
• Category: Amino Acids
• Molecular Weight: 401.45
• Molecular Formula: C25H23NO4
• Description: Building block for introduction of N-α-methyl-phenylalanine amino-acid residues by Fmoc SPPS.
• Synonyms: Fmoc-N-Me-Phe-OH, N-α-Fmoc-N-α-methyl-L-phenylalanine
• InChI: 1S/C25H23NO4/c1-26(23(24(27)28)15-17-9-3-2-4-10-17)25(29)30-16-22-20-13-7-5-11-18(20)19-12-6-8-14-21(19)22/h2-14,22-23H,15-16H2,1H3,(H,27,28)/t23-/m0/s1
• InChI Key: GBROUWPNYVBLFO-QHCPKHFHSA-N
• Application: Peptide synthesis.
• Assay: ≥97.0% (acidimetric); ≥98% (TLC); ≥98.0% (HPLC)
• Form: powder
• Functional Group: Fmoc
• MDL Number: MFCD00151938
• Quality Level: 200
• Reaction Suitability: reaction type: Fmoc solid-phase peptide synthesis
• Storage Temperature: 2-30℃
• Type: Unusual Amino Acids, N-α-Methyl Amino Acids

Synthetic Use

Upstream Synthesis Route 1

• 84000-03-3

• 77128-73-5

Reference: [1] Journal of Organic Chemistry, 2005, vol. 70, # 17, p. 6918 - 6920

Upstream Synthesis Route 2

• 2566-30-5
• 28920-43-6

• 77128-73-5

Reference: [1] Journal of Organic Chemistry, 1991, vol. 56, # 15, p. 4615 - 4625
[2] Biochemistry, 2010, vol. 49, # 10, p. 2177 - 2185

Upstream Synthesis Route 3

• 1208119-54-3
• 28920-43-6

• 77128-73-5

Reference: [1] Journal of Organic Chemistry, 2010, vol. 75, # 5, p. 1386 - 1392