Specification
Description
Fmoc-selenomethionine can be introduced under standard conditions. Any selenoxide formed during synthesis can be easily reduced back to selenide by treatment with β-mercaptoethanol. Introduction of selenium can help facilitate solid phase and solution structural determination and the study of peptide-protein interactions.
Synonyms
Fmoc-selenomethionine, N-Fmoc-L-amino-4-(methylselanyl)butanoic acid
InChI
1S/C20H21NO4Se/c1-26-11-10-18(19(22)23)21-20(24)25-12-17-15-8-4-2-6-13(15)14-7-3-5-9-16(14)17/h2-9,17-18H,10-12H2,1H3,(H,21,24)(H,22,23)/t18-/m0/s1
InChI Key
MOIJGLAOGAWHTN-SFHVURJKSA-N
Application
Fmoc solid-phase peptide synthesis.
Type
Unusual Amino Acids, Analogs of Cysteine and Methionine