Fmoc-Hse(Trt)-OH

• CAS: 111061-55-3
• Catalog Number: ACM111061553
• Category: Amino Acids
• Molecular Weight: 583.67
• Description: Building block which enables side-chain modification of homoserine serines by Fmoc SPPS. The Trt group can be removed with 1% TFA in DCM containing 5% TIS, enabling the side-chain hydroxyl group to be selectively modified whilst the derivative is attached to the solid support. This derivative has been employed to prepare oligonucleotide conjugates.
• Synonyms: Fmoc-Hse(Trt)-OH, N-α-Fmoc-O-trityl-L-homoserine
• InChI: 1S/C38H33NO5/c40-36(41)35(39-37(42)43-26-34-32-22-12-10-20-30(32)31-21-11-13-23-33(31)34)24-25-44-38(27-14-4-1-5-15-27,28-16-6-2-7-17-28)29-18-8-3-9-19-29/h1-23,34-35H,24-26H2,(H,39,42)(H,40,41)/t35-/m0/s1
• InChI Key: QUTREFXHXPNEJN-DHUJRADRSA-N
• Application: Peptide synthesis.
• Assay: ≥80.0% (acidimetric); ≥98% (TLC); ≥98.0% (HPLC)
• Form: powder
• Functional Group: hydroxyl
• MDL Number: MFCD00270544
• Quality Level: 200
• Reaction Suitability: reaction type: Fmoc solid-phase peptide synthesis
• Storage Temperature: 15-25℃