Fmoc-δ-azidonorvaline

• CAS: 1097192-04-5
• Catalog Number: ACM1097192045-1
• Category: Amino Acids
• Molecular Weight: 380.4
• Molecular Formula: C20H20N4O4
• Description: A useful tool for the synthesis of branched, side-chain modified, cyclic peptides and peptide tools for click chemistry by Fmoc SPPS. The side-chain azido group is completely stable to piperidine and TFA, but can be readily converted to an amine on the solid phase or in solution by reduction with thiols or phosphines. Guide to Selection of Orthogonally-Protected Building Blocks for Fmoc SPPS Literature references M. Meldal, et al. (1997) Tetrahedron Lett., 38, 2531. J. T. Lundquist & J. C. Pelletier (2001) Org. Lett., 3, 781. N. Nepomniaschiy, et al. (2008) Org. Lett., 10, 5243.
• Synonyms: Fmoc-δ-azidonorvaline, (2S)-N-Fmoc-5-azido-pentanoic acid
• InChI: 1S/C20H20N4O4/c21-24-22-11-5-10-18(19(25)26)23-20(27)28-12-17-15-8-3-1-6-13(15)14-7-2-4-9-16(14)17/h1-4,6-9,17-18H,5,10-12H2,(H,23,27)(H,25,26)/t18-/m0/s1
• InChI Key: TVPIDQLSARDIPX-SFHVURJKSA-N
• Application: Peptide synthesis.
• Assay: ≥95.0% (HPLC)
• Form: powder
• Functional Group: azide
• MDL Number: MFCD11052921
• Quality Level: 200
• Reaction Suitability: reaction type: Fmoc solid-phase peptide synthesis
• Storage Temperature: 15-25℃
• Type: Unusual Amino Acids, Azide and Alkyne containing Amino Acids