Structure

Fmoc-Gln-OH

CAS
71989-20-3
Catalog Number
ACM71989203
Category
Amino Acids
Molecular Weight
368.38

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Specification

Description
Building block for introduction of glutamine by Fmoc SPPS. Not compatible with uronium and phosphonium coupling reagents
Synonyms
Fmoc-Gln-OH, N-α-Fmoc-L-glutamine
InChI
1S/C20H20N2O5/c21-18(23)10-9-17(19(24)25)22-20(26)27-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16-17H,9-11H2,(H2,21,23)(H,22,26)(H,24,25)
InChI Key
IZKGGDFLLNVXNZ-UHFFFAOYSA-N
Melting Point
220-225℃
Application
Peptide synthesis.
Assay
≥95.0% (acidimetric)
≥98% (TLC)
≥99.0% (HPLC)
Form
powder
Functional Group
amide
MDL Number
MFCD00037137
Quality Level
200
Reaction Suitability
reaction type: Fmoc solid-phase peptide synthesis
Storage Temperature
2-30℃

Upstream Synthesis Route 1

  • 56-85-9
  • 71989-20-3

Reference: [1] Tetrahedron Letters, 2017, vol. 58, # 16, p. 1600 - 1603

Downstream Synthesis Route 1

  • 76-84-6
  • 71989-20-3
  • 132327-80-1

Reference: [1] Patent: US5354843, 1994, A,

Downstream Synthesis Route 2

  • 71989-20-3
  • 64-19-7
  • 2490-97-3

Reference: [1] Asian Journal of Chemistry, 2014, vol. 26, # 10, p. 2941 - 2944

* For details of the synthesis route, please refer to the original source to ensure accuracy.

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