Specification
Description
The side-chain Mtt group can be selectively removed with 1% TFA in DCM or DCM/HFIP/TFE/TES (6.5:2:1:0.5) , making this an excellent derivative for the synthesis of branched peptides and peptides modified at the Dpr side-chain , and for the construction of templates and multifunctionalized resins for combinatorial synthesis.
Synonyms
Fmoc-Dpr(Mtt)-OH, N-α-Fmoc-N-β-4-methyltrityl-L-diaminopropionic acid
InChI
1S/C38H34N2O4/c1-26-20-22-29(23-21-26)38(27-12-4-2-5-13-27,28-14-6-3-7-15-28)39-24-35(36(41)42)40-37(43)44-25-34-32-18-10-8-16-30(32)31-17-9-11-19-33(31)34/h2-23,34-35,39H,24-25H2,1H3,(H,40,43)(H,41,42)/t35-/m0/s1
InChI Key
WDZDBCVDBMWMAM-DHUJRADRSA-N
Application
Peptide synthesis.
Assay
≥95% (TLC)
≥95.0% (HPLC)
Reaction Suitability
reaction type: Fmoc solid-phase peptide synthesis
Storage Temperature
15-25℃