Fmoc-D-Glu(OtBu)-OH

• CAS: 104091-08-9
• Catalog Number: ACM104091089
• Category: Amino Acids
• Molecular Weight: 425.47
• Molecular Formula: C24H27NO6
• Description: Standard building block of introduction of D-glutamic acid amino-acid residues by Fmoc SPPS.
• Synonyms: Fmoc-D-glutamic acid 5-tert-butyl ester
• Canonical SMILES: CC(C)(C)OC(=O)CC[C@@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O
• InChI: 1S/C24H27NO6/c1-24(2,3)31-21(26)13-12-20(22(27)28)25-23(29)30-14-19-17-10-6-4-8-15(17)16-9-5-7-11-18(16)19/h4-11,19-20H,12-14H2,1-3H3,(H,25,29)(H,27,28)/t20-/m1/s1
• InChI Key: OTKXCALUHMPIGM-HXUWFJFHSA-N
• Melting Point: 86-96℃
• Application: Peptide synthesis.
• Assay: ≥98.0% (HPLC)
• Color: white
• Form: powder
• Functional Group: Fmoc
• MDL Number: MFCD00077055
• NACRES: NA.26
• Optical Activity: [α]/D +4.5±1, c = 1 in acetic acid: water (4:1)
• PubChem ID: 329748508
• Quality Level: 100
• Reaction Suitability: reaction type: Fmoc solid-phase peptide synthesis
• Storage Temperature: 2-8℃

Synthetic Use

Upstream Synthesis Route 1

• 104091-07-8

• 104091-08-9

Reference: [1] Journal of Organic Chemistry, 1986, vol. 51, # 24, p. 4590 - 4594

Upstream Synthesis Route 2

• 28920-43-6
• 45125-00-6

• 104091-08-9

Reference: [1] Journal of Organic Chemistry, 1986, vol. 51, # 24, p. 4590 - 4594

Upstream Synthesis Route 3

• 104091-09-0

• 104091-08-9

Reference: [1] Journal of Organic Chemistry, 1986, vol. 51, # 24, p. 4590 - 4594

Upstream Synthesis Route 4

• 28920-43-6
• 45125-00-6

• 104091-08-9

Reference: [1]Journal of Organic Chemistry,1986,vol. 51,p. 4590 - 4594

Downstream Synthesis Route 1

• 2592-95-2
• 104091-08-9

• 124007-49-4

Reference: [1]Journal of Organic Chemistry,1986,vol. 51,p. 4590 - 4594

* For details of the synthesis route, please refer to the original source to ensure accuracy.