Fmoc-D-Glu-OtBu

• CAS: 104091-08-9
• Catalog Number: ACM104091089-1
• Category: Amino Acids
• Molecular Weight: 425.5
• Molecular Formula: C24H27NO6
• Synonyms: Fmoc-D-Glu(OtBu)-OH, N-α-Fmoc-D-glutamic acid γ-t.-butyl ester
• IUPAC Name: (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoic acid
• InChI: 1S/C24H27NO6/c1-24(2,3)31-21(26)13-12-20(22(27)28)25-23(29)30-14-19-17-10-6-4-8-15(17)16-9-5-7-11-18(16)19/h4-11,19-20H,12-14H2,1-3H3,(H,25,29)(H,27,28)/t20-/m1/s1
• InChI Key: OTKXCALUHMPIGM-HXUWFJFHSA-N
• Boiling Point: 633.5±55.0 ℃at 760 mmHg
• Melting Point: 80-95 ℃
• Flash Point: 337.0±31.5 ℃
• Density: 1.2±0.1 g/cm³
• Solubility: Clearly soluble (1 mmole in 2 ml DMF)
• Application: Fmoc solid-phase peptide synthesis
• Assay: ≥92.0% (acidimetric); ≥98% (TLC); ≥98.0% (HPLC)
• Exact Mass: 425.183838
• Form: powder
• Functional Group: carboxylic acid
• Impurity Content: Water ≤ 6.0 %
• LogP: 5.26
• MDL Number: MFCD00077055
• PSA: 101.93
• Refractive Index: 1.571
• Storage Temperature: 2-30℃
• Type: Unlabeled Standard Amino Acids, Glutamic Acid (Glu)
• Vapor Pressure: 0.0±2.0 mmHg at 25℃
• WGK Germany: 3

Synthetic Use

Upstream Synthesis Route 1

• 104091-07-8

• 104091-08-9

Reference: [1] Journal of Organic Chemistry, 1986, vol. 51, # 24, p. 4590 - 4594

Upstream Synthesis Route 2

• 28920-43-6
• 45125-00-6

• 104091-08-9

Reference: [1] Journal of Organic Chemistry, 1986, vol. 51, # 24, p. 4590 - 4594

Upstream Synthesis Route 3

• 104091-09-0

• 104091-08-9

Reference: [1] Journal of Organic Chemistry, 1986, vol. 51, # 24, p. 4590 - 4594

Upstream Synthesis Route 4

• 28920-43-6
• 45125-00-6

• 104091-08-9

Reference: [1]Journal of Organic Chemistry,1986,vol. 51,p. 4590 - 4594

Downstream Synthesis Route 1

• 2592-95-2
• 104091-08-9

• 124007-49-4

Reference: [1]Journal of Organic Chemistry,1986,vol. 51,p. 4590 - 4594

* For details of the synthesis route, please refer to the original source to ensure accuracy.