Structure

Fmoc-Cys(Acm)-OH

CAS
86060-81-3
Catalog Number
ACM86060813
Category
Amino Acids
Molecular Weight
414.47

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Specification

Description
The side-chain Acm group is stable to TFA but can be removed with Hg(II) or Ag(I) to give cysteinyl peptides, or oxidatively with Tl(III) or I2 to generate cystinyl peptides.
Synonyms
Fmoc-Cys(Acm)-OH, N-α-Fmoc-S-acetamidomethyl-L-cysteine
InChI
1S/C21H22N2O5S/c1-13(24)22-12-29-11-19(20(25)26)23-21(27)28-10-18-16-8-4-2-6-14(16)15-7-3-5-9-17(15)18/h2-9,18-19H,10-12H2,1H3,(H,22,24)(H,23,27)(H,25,26)/t19-/m0/s1
InChI Key
CSMYOORPUGPKAP-IBGZPJMESA-N
Melting Point
147-150℃
Application
Peptide synthesis.
Assay
≥96.0% (acidimetric)
≥98% (TLC)
≥99.0% (HPLC)
Form
powder
Functional Group
thiol
MDL Number
MFCD00038769
Quality Level
200
Reaction Suitability
reaction type: Fmoc solid-phase peptide synthesis
Storage Temperature
2-30℃
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