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Etoposide phosphate (BMY-40481) is a potent anti-cancer chemotherapy agent and a selective topoisomerase II inhibitor?to prevent re-ligation of DNA strands. Etoposide phosphate is the phosphate ester proagent of etoposide and is considered as?active?equivalent to Etoposide. Etoposide phosphate induces cell cycle arrest,?apoptosis, and?autophagy.