Eriodictyol

• CAS: 552-58-9
• Catalog Number: ACM552589
• Category: Inhibitors
• Molecular Weight: 339.36
• Molecular Formula: C12H21NO8S
• Description: Eriodictyol is a flavonoid isolated from the Chinese herb, with antioxidant and anti-inflammatory activity. Eriodictyol induces Nrf2 signaling pathway. Eriodictyol is also a potent influenza RNA-dependent RNA polymerase inhibitor with an IC50 of 18 nM.
• Synonyms: (S)-3',4',5,7-Tetrahydroxyflavanone
• IUPAC Name: (2S)-2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydrochromen-4-one
• Canonical SMILES: C1C(OC2=CC(=CC(=C2C1=O)O)O)C3=CC(=C(C=C3)O)O
• InChI: InChI=1S/C15H12O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-5,13,16-19H,6H2/t13-/m0/s1
• InChI Key: SBHXYTNGIZCORC-ZDUSSCGKSA-N
• Boiling Point: 438.7±55.0 °C
• Melting Point: 125 °C
• Flash Point: 9 °C
• Density: 1.336±0.06 g/cm³
• Appearance: White solid
• Storage: 2-8 °C
• Complexity: 400
• Exact Mass: 288.06338810
• Hazard Statements: Xi
• Isomeric SMILES: C1[C@H](OC2=CC(=CC(=C2C1=O)O)O)C3=CC(=C(C=C3)O)O
• Monoisotopic Mass: 288.06338810
• pKa: 9.22±0.70(Predicted)
• Safety Description: 26-37/39
• Shipping: Can be shipped at room temperature, where not in use may vary.
• Source: Plantsother families
• Supplemental Hazard Statements: H315-H319-H335
• Symbol: GHS07
• Topological Polar Surface Area: 107 Ų

Custom Q&A

What is the molecular formula of Eriodictyol?

The molecular formula of Eriodictyol is C15H12O6.

What is the molecular weight of Eriodictyol?

The molecular weight of Eriodictyol is 288.25 g/mol.

What is the IUPAC name of Eriodictyol?

The IUPAC name of Eriodictyol is (2S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydrochromen-4-one.

What are some synonyms for Eriodictyol?

Some synonyms for Eriodictyol include ERIODICTYOL, 552-58-9, Eriodictiol, Huazhongilexone, and (+)-Eriodictyol.

Where is Eriodictyol naturally found?

Eriodictyol is a natural product found in Eupatorium album, Eupatorium hyssopifolium, and other organisms with data available.

What is the InChIKey of Eriodictyol?

The InChIKey of Eriodictyol is SBHXYTNGIZCORC-ZDUSSCGKSA-N.

How many hydrogen bond donor counts does Eriodictyol have?

Eriodictyol has 4 hydrogen bond donor counts.

What is the exact mass and monoistopic mass of Eriodictyol?

The exact mass and monoistopic mass of Eriodictyol are both 288.06338810 g/mol.

How many rotatable bond counts does Eriodictyol have?

Eriodictyol has 1 rotatable bond count.

What is the topological polar surface area of Eriodictyol?

The topological polar surface area of Eriodictyol is 107.2.

Synthetic Use

Upstream Synthesis Route 1

• 480-18-2

• 552-58-9

Reference: [1]Journal of the Chemical Society. Perkin transactions I,1980,p. 1003 - 1006

Downstream Synthesis Route 1

• 485-80-3
• 552-58-9

• 520-33-2

Reference: [1] FEBS Letters, 2016, p. 2619 - 2628

Downstream Synthesis Route 2

• 108-24-7
• 552-58-9

• 10210-16-9

Reference: [1]Journal of the American Chemical Society,1948,vol. 70,p. 3031,3033 Anm. 25
Journal of Organic Chemistry,1962,vol. 27,p. 2935
[2]European Journal of Pharmacology,2006,vol. 548,p. 9 - 20

Downstream Synthesis Route 3

• 108-24-7
• 552-58-9

• 6599-89-9

Reference: [1]Journal of the American Chemical Society,1948,vol. 70,p. 3031,3033 Anm. 25
Journal of Organic Chemistry,1962,vol. 27,p. 2935

* For details of the synthesis route, please refer to the original source to ensure accuracy.