Albendazole

• CAS: 54965-21-8
• Catalog Number: ACM54965218
• Category: Inhibitors
• Molecular Weight: 265.33
• Molecular Formula: C12H15N3O2S
• Description: Albendazole, marketed as Albenza among others, is medication used for the treatment of a variety of parasitic worm infestations. It is useful for giardiasis, trichuriasis, filariasis, neurocysticercosis, hydatid disease, pinworm disease, and ascariasis, among others. It is taken by mouth.Common side effects include nausea, abdominal pains, and headaches. Potentially serious side effects include bone marrow suppression which usually improves on stopping the medication. Liver inflammation has been reported and those with prior liver problems are at greater risk. It is pregnancy category C in the United States and category D in Australia, meaning it may cause harm if taken by a pregnant women. Albendazole is a broad-spectrum antihelminthic agent of the benzimidazole type.Albendazole developed in 1975. It is on the World Health Organization’s List of Essential Medicines, the most important medications needed in a basic health system. The wholesale cost in the developing world is between 0.01 and 0.06 USD per dose. In the United States, however, it is very expensive as of 2014 at about 50 USD per dose.
• Synonyms: [5-(PROPYLTHIO)-1H-BENZIMIDAZOL-2-YL]CARBAMIC ACID, METHYL ESTER;[5-(PROPYLTHIO)BENZIMIDAZOL-2-YL]CARBAMIC ACID METHYL ESTER;(5-PROPYLSULFANYL-1H-BENZOIMIDAZOL-2-YL)-CARBAMIC ACID METHYL ESTER;ALBAZINE;ALBEN;ALBENDAZOLE;ALBENZA;AKOS NCG1-0064
• Canonical SMILES: O=C(OC)NC1=NC2=CC=C(SCCC)C=C2N1
• Melting Point: 208-210 °C
• Appearance: Colourless crystalline solid
• Storage: Powder-20°C, 3 years; 4°C, 2 years; In solvent-80°C, 6 months; -20°C, 1 month.
• Hazard Codes: T
• Hazard Statements: T,Xn
• HS Code: 3004909090
• LogP: 3.31630
• MDL Number: MFCD00083232
• PSA: 92.31
• Safety Description: 53-45-37/39-26-36/37
• Shipping: Can be shipped at room temperature, where not in use may vary.
• Storage Conditions: 0-6°C
• Supplemental Hazard Statements: H302-H361-H373-H312+H332-H360
• Symbol: GHS07,GHS08
• WGK Germany: 2

Custom Q&A

What is the molecular formula of albendazole?

The molecular formula of albendazole is C12H15N3O2S.

What are some synonyms for albendazole?

Some synonyms for albendazole include Albenza, Eskazole, and Zentel.

What is the molecular weight of albendazole?

The molecular weight of albendazole is 265.33 g/mol.

What is the role of albendazole in the treatment of parasitic worm infestations?

Albendazole has a role as a tubulin modulator, a microtubule-destabilising agent, and an anthelminthic drug in the treatment of parasitic worm infestations.

What types of parasitic infections is albendazole approved to treat by the U.S. FDA?

Albendazole is approved by the U.S. FDA for the treatment of neurocysticercosis, hydatid disease, and microsporidiosis.

What is the IUPAC name of albendazole?

The IUPAC name of albendazole is methyl N-(6-propylsulfanyl-1H-benzimidazol-2-yl)carbamate.

What is the InChIKey of albendazole?

The InChIKey of albendazole is HXHWSAZORRCQMX-UHFFFAOYSA-N.

What is the Canonical SMILES representation of albendazole?

The Canonical SMILES representation of albendazole is CCCSC1=CC2=C(C=C1)N=C(N2)NC(=O)OC.

What is the European Community (EC) Number for albendazole?

The European Community (EC) Number for albendazole is 259-414-7.

What is the XLogP3 value of albendazole?

The XLogP3 value of albendazole is 2.9.