E3330

CAS
136164-66-4
Catalog Number
ACM136164664
Category
Inhibitors
Molecular Weight
378.46
Molecular Formula
C21H30O6

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Specification

Description
E3330 (APX-3330) is a direct, orally active and selective inhibitor of Ape-1 (apurinic/apyrimidinic endonuclease 1)/Ref-1 (redox factor-1) redox. E3330 is able to impair tumor growth and blocks the activity of NF-κB, AP-1, and HIF-1α in pancreatic cancer. E3330 shows anticancer activities.
Canonical SMILES
CCCCCCCCC/C(C(O)=O)=C\C1=C(C)C(C(OC)=C(OC)C1=O)=O
Appearance
Solid
Storage
Powder-20°C, 3 years; 4°C, 2 years; In solvent-80°C, 6 months; -20°C, 1 month.
Shipping
Can be shipped at room temperature, where not in use may vary.
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