CAS
136164-66-4 Purity
99.34%
136164-66-4 Purity
99.34%
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Cambinol
CAS
14513-15-6
Catalog Number
ACM14513156
Category
Inhibitors
Molecular Weight
360.43
Molecular Formula
C21H16N2O2S
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Specification
Description
Cambinol is a SIRT1 and SIRT2 inhibitor with IC50 values of 56 μM and 59 μM, respectively. Cambinol is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor).
Synonyms
cambinol, NSC112546, NSC-112546, SIRT1/2 Inhibitor IV, Cambinol, 14513-15-6, 5-(2-Hydroxy-naphthalen-1-ylmethyl)-6-phenyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one, AC1MMYEF, NCIStruc1_001428, NCIStruc2_001159, SureCN3332758, CHEMBL491960, CTK8G3107, HMS3261K21, CCG-37240, DNC009417, NCGC00014121, NCI112546, AKOS002364304, AG-D-88787, CCG-221684
IUPAC Name
5-[(2-hydroxynaphthalen-1-yl)methyl]-6-phenyl-2-sulfanylidene-1H-pyrimidin-4-one
InChI Key
RVNSQVIUFZVNAU-UHFFFAOYSA-N
Boiling Point
667ºC at 760mmHg
Flash Point
357.2ºC
Density
1.41g/cm³
Exact Mass
360.09300
Hazard Statements
Xn: Harmful;
H-Bond Acceptor
3
H-Bond Donor
3
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