3,4-Dihydroxy-L-phenylalanine

• CAS: 59-92-7
• Catalog Number: ACM59927-2
• Category: Amino Acids
• Molecular Weight: 197.19
• Molecular Formula: (HO)2C6H3CH2CH(NH2)CO2H
• Synonyms: 3-(3,4-Dihydroxyphenyl)-L-alanine, L-3-Hydroxytyrosine, L-DOPA, Levodopa
• Canonical SMILES: N[C@@H](Cc1ccc(O)c(O)c1)C(O)=O
• InChI: 1S/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14)/t6-/m0/s1
• InChI Key: WTDRDQBEARUVNC-LURJTMIESA-N
• Melting Point: 276-278 ℃(lit.)
• Application: 3,4-Dihydroxy-L-phenylalanine or L-DOPA has been used to stain melanocytes. It has also been used to study its effects on a Drosophila model of Parkinson's disease.
• Assay: ≥98% (TLC)
• Beilstein: 2215169
• Biochem Physiol Actions: 3,4-Dihydroxy-L-phenylalanine or L-DOPA is a natural isomer of the immediate precursor of dopamine that crosses the blood-brain barrier. It is used for the treatment of Parkinson's disease and is a product of tyrosine hydroxylase.
• Color: white to off-white
• EC Number: 200-445-2
• Form: powder
• Gene Information: human DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816); mouse DRD1(13488), DRD2(13489), DRD3(13490), DRD4(13491), DRD5(13492); rat DRD1(24316), DRD2(24318), DRD3(29238), DRD4(25432), DRD5(25195)
• MDL Number: MFCD00002598
• NACRES: NA.32
• PubChem ID: 24277914
• Quality Level: 200
• Storage Temperature: Store at room temperature