Dihydrocoumarin

• CAS: 119-84-6
• Catalog Number: ACM119846
• Category: Inhibitors
• Molecular Weight: 148.16
• Molecular Formula: C9H8O2
• Description: Dihydrocoumarin is a compound found in Melilotus officinalis. Dihydrocoumarin is a yeast Sir2p inhibitor. Dihydrocoumarin also inhibits human SIRT1 and SIRT2 with IC50s of 208 μM and 295 μM, respectively.
• Synonyms: 3,4-Dihydrocoumarin
• IUPAC Name: 3,4-dihydrochromen-2-one
• Canonical SMILES: C1CC(=O)OC2=CC=CC=C21
• InChI: VMUXSMXIQBNMGZ-UHFFFAOYSA-N
• InChI Key: InChI=1S/C9H8O2/c10-9-6-5-7-3-1-2-4-8(7)11-9/h1-4H,5-6H2
• Boiling Point: 272 °C (lit.)
• Melting Point: 24-25 °C (lit.)
• Density: 1.169g/ml
• Active Content: 95%
• Physical State: Solid/Liquid

Custom Q&A

What is the CAS number for Dihydrocoumarin?

The CAS number for Dihydrocoumarin is 119-84-6.

What are some synonyms for Dihydrocoumarin?

Some synonyms for Dihydrocoumarin are 3,4-Dihydrocoumarin and 3,4-dihydrochromen-2-one.

What is the molecular weight of Dihydrocoumarin?

The molecular weight of Dihydrocoumarin is 148.16.

What is the molecular formula of Dihydrocoumarin?

The molecular formula of Dihydrocoumarin is C9H8O2.

What is the boiling point of Dihydrocoumarin?

The boiling point of Dihydrocoumarin is 272°C (lit.).

What is the melting point of Dihydrocoumarin?

The melting point of Dihydrocoumarin is 24-25°C (lit.).

What is the purity of Dihydrocoumarin?

The purity of Dihydrocoumarin is 99%.

What is the density of Dihydrocoumarin?

The density of Dihydrocoumarin is 1.169g/ml.

What is the percentage of actives in Dihydrocoumarin?

The percentage of actives in Dihydrocoumarin is 95%.

What are some typical applications of Dihydrocoumarin?

Some typical applications of Dihydrocoumarin include its use in perfume.

Synthetic Use

Upstream Synthesis Route 1

• 91-64-5

• 4430-31-3
• 701-97-3
• 20349-89-7
• 63714-95-4
• 119-84-6
• 501-52-0

Reference: [1] Chinese Journal of Catalysis, 2015, vol. 36, # 7, p. 957 - 960

Upstream Synthesis Route 2

• 91-64-5

• 119-84-6

Reference: [1]Elamin, Babiker; Park, Jeen-Woo; Means, Gary E.
[Tetrahedron Letters, 1988, vol. 29, # 44, p. 5599 - 5600]

Downstream Synthesis Route 1

• 119-84-6

• 1076-38-6
• 2669-94-5
• 495-78-3
• 1318928-52-7
• 1481-92-1
• 20349-89-7

Reference: [1] Arkivoc, 2011, vol. 2011, # 7, p. 170 - 181

Downstream Synthesis Route 2

• 119-84-6

• 20921-00-0

Reference: [1] Journal of Organometallic Chemistry, 1990, vol. 387, # 3, p. 381 - 390

Downstream Synthesis Route 3

• 119-84-6

• 19063-55-9

Reference: [1]Hagen, James P.
[Journal of Organic Chemistry, 1993, vol. 58, # 2, p. 506 - 508]
[2]Ito; Kitagawa
[Yakugaku Zasshi/Journal of the Pharmaceutical Society of Japan, 1953, vol. 73, p. 107][Chem.Abstr., 1953, p. 11187]
[3]Lee, Hyeon Kyu; Kim, Jia; Pak, Chwang Siek
[Tetrahedron Letters, 1999, vol. 40, # 34, p. 6267 - 6270]

* For details of the synthesis route, please refer to the original source to ensure accuracy.