Dde-Lys(Fmoc)-OH

• CAS: 156648-40-7
• Catalog Number: ACM156648407
• Category: Amino Acids
• Molecular Weight: 532.63
• Description: Quasi-orthogonally-protected Lys derivative. The Fmoc group can be removed selectively by treatment with piperidine; the Dde group is cleaved with 2% hydrazine in DMF. When removing Dde in the presence of allyl-based protecting groups, allyl alcohol should be included in the deprotection solution to prevent reduction of the allyl group. Also available Fmoc-Lys(Dde)-OH 852057. This derivative has been employed in Fmoc SPPS to facilitate the introduction of biotin to the side-chain of lysine.
• Synonyms: Dde-Lys(Fmoc)-OH, N-α-1-(4,4-Dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl-N-ε-Fmoc-L-lysine
• Melting Point: >70 ℃(decomposition)
• Application: Peptide synthesis.
• Assay: ≥90.0% (acidimetric); ≥96.0% (HPLC); ≥97% (TLC)
• Form: powder
• Functional Group: amine
• Quality Level: 200
• Reaction Suitability: reaction type: Fmoc solid-phase peptide synthesis
• Storage Temperature: 15-25℃