Cinchonidine

• CAS: 485-71-2
• Catalog Number: ACM485712
• Category: Inhibitors
• Molecular Weight: 294.39
• Molecular Formula: C19H22N2O
• Description: Cinchonidine (α-Quinidine) is a cinchona alkaloid found in Cinchona officinalis and Gongronema latifolium. A building block used in asymmetric synthesis in organic chemistry. Weak inhibitor of serotonin transporter (SERT) with Kis of 330, 4.2, 36, 196, 15 μM for dSERT, hSERT, hSERT I172M, hSERT S438T, hSERT Y95F, respectively. Antimalarial activities.
• Synonyms: Cinchonidinederivedcatalyst
• IUPAC Name: (R)-[(2S,4S,5R)-5-Ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-quinolin-4-ylmethanol
• Canonical SMILES: C=CC1CN2CCC1CC2C(C3=CC=NC4=CC=CC=C34)O
• InChI: InChI=1S/C19H22N2O/c1-2-13-12-21-10-8-14(13)11-18(21)19(22)16-7-9-20-17-6-4-3-5-15(16)17/h2-7,9,13-14,18-19,22H,1,8,10-12H2/t13-,14-,18-,19+/m0/s1
• InChI Key: KMPWYEUPVWOPIM-KODHJQJWSA-N
• Boiling Point: 436.16 °C
• Melting Point: 204-206 °C(lit.)
• Flash Point: 234.7 °C
• Density: 1.0863 g/cm³
• Solubility: Insoluble in water
• Appearance: Crystalline powder
• Application: Occurs in most varieties of Cinchona
• Storage: Keep in dark place, inert atmosphere, room temperature
• Active Content: 95%
• Complexity: 412
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 4
• EC Number: 207-622-3
• Exact Mass: 294.173213330
• H-Bond Acceptor: 3
• H-Bond Donor: 1
• Heavy Atom Count: 22
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• Isomeric SMILES: C=C[C@H]1CN2CC[C@H]1C[C@H]2[C@@H](C3=CC=NC4=CC=CC=C34)O
• Monoisotopic Mass: 294.173213330
• NSC Number: 757800
• Physical State: Crystalline powder
• Rotatable Bond Count: 3
• Topological Polar Surface Area: 36.4 Ų
• UNII: 1U622LRA8Z

Custom Q&A

What is the synonym for Cinchonidine?

Cinchonan-9-ol.

What is the IUPAC name for Cinchonidine?

(R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-quinolin-4-ylmethanol.

What is the molecular weight of Cinchonidine?

294.4.

What is the molecular formula of Cinchonidine?

C19H22N2O.

What is the boiling point of Cinchonidine?

464.5 °C / 760 mmHg.

What is the melting point of Cinchonidine?

204-206 °C.

What is the purity of Cinchonidine?

98%+.

What is the typical physical state of Cinchonidine?

Crystalline powder.

What is the typical application of Cinchonidine?

Use as an intermediate in organic synthesis.

What is the storage recommendation for Cinchonidine?

Sealed in dry. Keep in a dark place. Room temperature.