CGP52411

• CAS: 145915-58-8
• Catalog Number: ACM145915588-1
• Category: Inhibitors
• Molecular Weight: 329.36
• Molecular Formula: C20H15N3O2
• Description: CGP52411, also known as DAPH, is a selective inhibitor of the epidermal growth factor receptor (EGFR). It is also inhibits and reverses the formation of Aβ42 fibers associated with Alzheimer's disease. It may offer therapeutic agents for the treatment of hyperproliferative diseases.
• Synonyms: CGP52411; CGP 52411; CGP-52411; DAPH
• IUPAC Name: 5,6-bis(phenylamino)isoindoline-1,3-dione
• Canonical SMILES: O=C1NC(C2=CC(NC3=CC=CC=C3)=C(C=C21)NC4=CC=CC=C4)=O
• InChI: InChI=1S/C20H15N3O2/c24-19-15-11-17(21-13-7-3-1-4-8-13)18(12-16(15)20(25)23-19)22-14-9-5-2-6-10-14/h1-12,21-22H,(H,23,24,25)
• InChI Key: AAALVYBICLMAMA-UHFFFAOYSA-N
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Shelf Life: >3 years if stored properly
• Storage: Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).
• Drug Formulation: This drug may be formulated in DMSO
• Elemental Analysis: C, 72.94; H, 4.59; N, 12.76; O, 9.72
• Exact Mass: 329.1164
• HS Tariff Code: 2934.99.9001
• Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
• Stock Solution Storage: 0-4 °C for short term (days to weeks), or -20 °C for long term (months).