Structure

Cefotaxime sodium

CAS
64485-93-4
Catalog Number
ACM64485934
Category
Inhibitors
Molecular Weight
477.45
Molecular Formula
C16H16N5NaO7S2

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Specification

Description
Broad spectrum third generation cephalosporin antibiotic. The name Cefotaxime applies to the isomer having a syn-methoxy imino group.
Synonyms
hr756;Cefotaxime Na;sodium cefotaxime;Tolycar;FIR-756
Melting Point
162-163ºC(lit.)
Density
1.8 g/cm³
Appearance
White to pale yellow crystalline powder
Hazard Codes
Xn
Hazard Statements
Xn,Xi
HS Code
29419000
LogP
-1.04720
PSA
229.88
Safety Description
22-36/37
Stability
Stable. Incompatible with strong oxidizing agents.
Storage Conditions
2-8ºC
Supplemental Hazard Statements
H317-H334
Symbol
GHS08
WGK Germany
2
What is the molecular formula of cefotaxime sodium according to the reference?

The molecular formula of cefotaxime sodium is C16H16N5NaO7S2.

What is the molecular weight of cefotaxime sodium?

The molecular weight of cefotaxime sodium is 477.5 g/mol.

What are some synonyms for cefotaxime sodium?

Some synonyms for cefotaxime sodium are Sodium cefotaxime and CEFOTAXIME SODIUM SALT.

How does cefotaxime sodium work as an antibiotic?

Cefotaxime sodium binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall, interfering with the cross-linking of peptidoglycan chains necessary for bacterial cell wall strength and rigidity, ultimately causing cell lysis.

What type of bacteria is cefotaxime sodium more active against?

Cefotaxime sodium is more active against gram-negative bacteria compared to gram-positive bacteria.

What is the IUPAC Name of cefotaxime sodium?

The IUPAC Name of cefotaxime sodium is sodium;(6R,7R)-3-(acetyloxymethyl)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate.

What is the InChIKey of cefotaxime sodium?

The InChIKey of cefotaxime sodium is AZZMGZXNTDTSME-JUZDKLSSSA-M.

What is the Canonical SMILES of cefotaxime sodium?

The Canonical SMILES of cefotaxime sodium is CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)C(=NOC)C3=CSC(=N3)N)SC1)C(=O)[O-].[Na+].

What is the CAS number for cefotaxime sodium?

The CAS number for cefotaxime sodium is 64485-93-4.

What property of cefotaxime sodium is computed to have a value of 8?

The Rotatable Bond Count of cefotaxime sodium is computed to have a value of 8.

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