Boc-Nalpha-methyl-N-im-trityl-L-histidine

• CAS: 1217610-35-9
• Catalog Number: ACM1217610359
• Category: Amino Acids
• Molecular Weight: 511.6
• Molecular Formula: C31H33N3O4
• Description: Boc-Nalpha-methyl-N-im-trityl-L-histidine is a compound that is widely used in the fields of chemistry and biochemistry. It is a derivative of the natural amino acid L-histidine, and is commonly referred to as Trt-His(Me)-OH. The compound is characterized by the presence of a protecting group known as Boc, which makes it stable and easy to handle. This protective group can be removed under mild conditions, enabling the incorporation of Boc-Nalpha-methyl-N-im-trityl-L-histidine into complex molecules. The compound is used in a variety of research applications including peptide synthesis, drug discovery, and biological studies.
• Synonyms: N-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-1-tritylhistidine
• IUPAC Name: (2S)-2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]-3-(1-tritylimidazol-4-yl)propanoic acid
• Canonical SMILES: CC(C)(C)OC(=O)N(C)C(CC1=CN(C=N1)C(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)C(=O)O
• InChI: 1S/C31H33N3O4/c1-30(2,3)38-29(37)33(4)27(28(35)36)20-26-21-34(22-32-26)31(23-14-8-5-9-15-23,24-16-10-6-11-17-24)25-18-12-7-13-19-25/h5-19,21-22,27H,20H2,1-4H3,(H,35,36)/t27-/m0/s1
• InChI Key: SWXYPSNTJGPVOJ-MHZLTWQESA-N
• Boiling Point: 651.0±55.0 ℃at 760 mmHg
• Flash Point: 347.5±31.5 ℃
• Density: 1.1±0.1 g/cm³
• Application: Boc-Nalpha-methyl-N-im-trityl-L-histidine has a wide range of applications in scientific research. It can be used in peptide synthesis to increase the solubility and stability of peptides. The compound can also be used as a protecting group during peptide synthesis to ensure the correct sequence of amino acids. Additionally, Boc-Nalpha-methyl-N-im-trityl-L-histidine has been used in the development of peptide-based drugs and as a tool for studying protein-protein interactions.
• Exact Mass: 511.247101
• Functional Group: Boc
• LogP: 6.08
• MDL Number: MFCD04974255
• Refractive Index: 1.585
• Storage Temperature: 4 ℃
• Type: Unusual Amino Acids, N-α-Methyl Amino Acids
• Vapor Pressure: 0.0±2.0 mmHg at 25℃