Boc-D-Lys-OH

• CAS: 106719-44-2
• Catalog Number: ACM106719442
• Category: Amino Acids
• Molecular Weight: 246.3
• Synonyms: Nα-(tert-Butoxycarbonyl)-D-lysine, Nα-Boc-D-lysine
• Canonical SMILES: OC([C@H](NC(OC(C)(C)C)=O)CCCCN)=O
• InChI: 1S/C11H22N2O4/c1-11(2,3)17-10(16)13-8(9(14)15)6-4-5-7-12/h8H,4-7,12H2,1-3H3,(H,13,16)(H,14,15)/t8-/m1/s1
• InChI Key: DQUHYEDEGRNAFO-MRVPVSSYSA-N
• Melting Point: 205-210℃
• Application: Peptide synthesis.
• Assay: 0.98
• Form: powder or crystals
• Functional Group: Boc
• MDL Number: MFCD00076956
• NACRES: NA.22
• Optical Activity: [α]22/D -24°, c = 0.5% in methanol
• PubChem ID: 329767956
• Quality Level: 100
• Reaction Suitability: reaction type: Boc solid-phase peptide synthesis
• Storage Temperature: 2-8℃

Synthetic Use

Upstream Synthesis Route 1

• 55878-47-2

• 106719-44-2

Reference: [1] Journal of Chemical Research, Miniprint, 1991, # 5, p. 914 - 934
[2] Journal of the American Chemical Society, 2014, vol. 136, # 31, p. 10874 - 10877

Upstream Synthesis Route 2

• 24424-99-5

• 106719-44-2

Reference: [1] Journal of Chemical Research, Miniprint, 1991, # 5, p. 914 - 934

Upstream Synthesis Route 3

• 55878-47-2

• 106719-44-2

Reference: [1]Journal of Chemical Research, Miniprint,1991,p. 914 - 934
[2]Journal of the American Chemical Society,2014,vol. 136,p. 10874 - 10877

Downstream Synthesis Route 1

• 106719-44-2
• 501-53-1

• 55878-47-2

Reference: [1] Journal of Medicinal Chemistry, 2016, vol. 59, # 5, p. 2222 - 2243
[2] Patent: WO2017/63910, 2017, A1, . Location in patent: Page/Page column 38-39

Downstream Synthesis Route 2

• 24690-42-4
• 106719-44-2

• 122546-52-5

Reference: [1]Journal of Chemical Research, Miniprint,1991,p. 914 - 934

Downstream Synthesis Route 3

• 106719-44-2
• 141789-87-9

• 135741-41-2

Reference: [1]Journal of Medicinal Chemistry,1991,vol. 34,p. 2928 - 2931

* For details of the synthesis route, please refer to the original source to ensure accuracy.