CAS
7681-54-1 Purity
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7681-54-1 Purity
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Bisantrene
CAS
78186-34-2
Catalog Number
ACM78186342
Category
Inhibitors
Molecular Weight
398.47
Molecular Formula
C22H22N8
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Specification
Description
Bisantrene is a highly effective antitumor agent, it exerts its cytotoxicity by affecting DNA intercalation. Bisantrene targets eukaryotic type II topoisomerases. Bisantrene is a substrate of MDR1.
Synonyms
Zantrene; 9,10-Anthracenedicarboxaldehyde bis(2-imidazolin-2-ylhydrazone); ADAH; BISANTRENE HCL; 9,10-Anthracenedicarbaldehyde bis[(4,5-dihydro-1H-imidazol-2-yl)hydrazone]; anthracene-9,10-dicarbaldehyde bis-imidazolidin-2-ylidenehydrazone; Orange Crush;
IUPAC Name
N-[(E)-[10-[(E)-(4,5-dihydro-1H-imidazol-2-ylhydrazinylidene)methyl]anthracen-9-yl]methylideneamino]-4,5-dihydro-1H-imidazol-2-amine
InChI Key
NJSMWLQOCQIOPE-OCHFTUDZSA-N
Boiling Point
646.3ºC at 760 mmHg
Flash Point
344.7ºC
Density
1.41g/cm³
Exact Mass
398.19700
H-Bond Acceptor
8
H-Bond Donor
4
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