Structure

Bilobalide

CAS
33570-04-6
Catalog Number
ACM33570046
Category
Inhibitors
Molecular Weight
326.3
Molecular Formula
C15H18O8

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Specification

Description
Bilobalide, a sesquiterpene trilactone constituent of Ginkgo biloba, inhibits the NMDA-induced efflux of choline with an IC50 value of 2.3 µM. Bilobalide prevents apoptosis through activation of the PI3K/Akt pathway in SH-SY5Y cells. Exerts protective and trophic effects on neurons.
Synonyms
(-)-Bilobalide
Canonical SMILES
CC(C)(C)[C@@]1(C[C@H]2[C@@]3([C@]14[C@H](C(=O)O[C@H]4OC3=O)O)CC(=O)O2)O
Boiling Point
651.74 °C at 760 mmHg (Predicted)
Active Content
95%
Physical State
Solid
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