Bafilomycin c1

• CAS: 88979-61-7
• Catalog Number: ACM88979617
• Category: Inhibitors
• Molecular Weight: 720.8865
• Molecular Formula: C₃₉H₆₀O₁₂
• Description: Bafilomycin C1 is a macrolide antibiotic isolated from Streptomyces sp. Bafilomycin C1 is a potent, specific and reversible inhibitor of vacuolar-type H+-ATPases (V-ATPases). Bafilomycin C1 inhibits growth of gram-positive bacteria and fungi. Bafilomycin C1 induces cell apoptosis and can be used for the study of hepatocellular carcinoma (HCC).
• Synonyms: BAFILOMYCIN C1;2-Demethyl-2-methoxy-24-methylhygrolidin;Antibiotic L-681110A1;L-681110A1
• IUPAC Name: 4-[2-hydroxy-2-[3-hydroxy-4-(10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxo-1-oxacyclohexadeca-4,6,12,14-tetraen-2-yl)pentan-2-yl]-5-methyl-6-propan-2-yloxan-4-yl]oxy-4-oxobut-2-enoic acid
• Canonical SMILES: CC1CC(=CC=CC(C(OC(=O)C(=CC(=CC(C1O)C)C)OC)C(C)C(C(C)C2(CC(C(C(O2)C(C)C)C)OC(=O)C=CC(=O)O)O)O)OC)C
• InChI Key: WUDBXVQNMOTFEE-UHFFFAOYSA-N
• Boiling Point: 844.4ºC at 760 mmHg
• Flash Point: 248.9ºC
• Density: 1.18 g/cm³
• Appearance: Light tan solid
• Exact Mass: 720.40800
• H-Bond Acceptor: 12
• H-Bond Donor: 4