Specification
Description
AGX51 is a first-in-class pan-Id antagonist, inhibiting pathologic ocular neovascularization and the Id1-E47 interaction, leading to ubiquitin-mediated degradation of Ids, cell growth arrest, and reduced viability.
Synonyms
AGX51; AGX-51; AGX 51
IUPAC Name
N-Benzyl-N-(3-(2,3-dihydrobenzofuran-6-yl)-3-(2-methoxyphenyl)propyl)propionamide
Canonical SMILES
CCC(N(CC1=CC=CC=C1)CCC(C2=CC=C3CCOC3=C2)C4=CC=CC=C4OC)=O
InChI
InChI=1S/C28H31NO3/c1-3-28(30)29(20-21-9-5-4-6-10-21)17-15-24(25-11-7-8-12-26(25)31-2)23-14-13-22-16-18-32-27(22)19-23/h4-14,19,24H,3,15-18,20H2,1-2H3
InChI Key
RPUIBPORFRUAAZ-UHFFFAOYSA-N
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Storage
Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).
Drug Formulation
This drug may be formulated in DMSO
Elemental Analysis
C, 78.29; H, 7.27; N, 3.26; O, 11.17
HS Tariff Code
2934.99.9001
Shipping
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Stock Solution Storage
0-4 °C for short term (days to weeks), or -20 °C for long term (months).