1,2:5,6-Di-O-isopropylidene-alpha-D-allofuranose

• CAS: 2595-05-3
• Catalog Number: ACM2595053
• Category: Other Products
• Molecular Weight: 260.28
• Molecular Formula: C12H20O6
• Synonyms: 1,2:5,6-Bis-O-(1-Methylethylidene)-α-D-allofuranose
• IUPAC Name: (3aR,5S,6R,6aR)-5-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-6-ol
• Canonical SMILES: CC1(OC[C@@H](O1)[C@@H]2[C@H]([C@@H]3[C@H](O2)OC(O3)(C)C)O)C
• InChI: InChI=1S/C12H20O6/c1-11(2)14-5-6(16-11)8-7(13)9-10(15-8)18-12(3,4)17-9/h6-10,13H,5H2,1-4H3/t6-,7-,8-,9-,10-/m1/s1
• InChI Key: KEJGAYKWRDILTF-VVULQXIFSA-N
• Melting Point: 73-76 °C (lit.)
• Density: 1.238 g/ml
• Appearance: White to off-white solid
• Physical Description: 1,2:5,6-Di-O-isopropylidene-a-D-allofuranose 98% (2.5g)
• pKa: 13.15±0.60
• Refractive Index: 36.5 ° (C=1, CHCl3)

Synthetic Use

Upstream Synthesis Route 1

• 2847-00-9

• 2595-05-3

Reference: [1] Synthesis, 2004, # 18, p. 2965 - 2974

Upstream Synthesis Route 2

• 582-52-5

• 2595-05-3

Reference: [1] Tetrahedron Letters, 2006, vol. 47, # 34, p. 6041 - 6044

Upstream Synthesis Route 3

• 2847-00-9

• 2595-05-3

Reference: [1]Synthesis,2004,p. 2965 - 2974

Downstream Synthesis Route 1

• 2595-05-3

• 63593-03-3

Reference: [1] Bioorganic and Medicinal Chemistry Letters, 2014, vol. 24, # 12, p. 2699 - 2702

Downstream Synthesis Route 2

• 2595-05-3

• 4495-04-9

Reference: [1]European Journal of Organic Chemistry,2013,p. 7941 - 7951

Downstream Synthesis Route 3

• 358-23-6
• 2595-05-3

• 55951-90-1

Reference: [1]Tetrahedron Letters,2019,vol. 60,p. 1830 - 1833

* For details of the synthesis route, please refer to the original source to ensure accuracy.