874779-56-3 Purity
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Specification
The molecular formula of JNJ-26481585 is C21H26N6O2.
JNJ-26481585 was first created on October 26, 2006.
The molecular weight of JNJ-26481585 is 394.5 g/mol.
Another name for JNJ-26481585 is Quisinostat.
JNJ-26481585 is a second-generation, hydroxamic acid-based inhibitor of histone deacetylase (HDAC) with potential antineoplastic activity.
JNJ-26481585 inhibits HDAC leading to an accumulation of highly acetylated histones, which may result in an induction of chromatin remodeling; inhibition of the transcription of tumor suppressor genes; inhibition of tumor cell division; and the induction of tumor cell apoptosis.
The InChIKey for JNJ-26481585 is PAWIYAYFNXQGAP-UHFFFAOYSA-N.
JNJ-26481585 has 3 hydrogen bond donor counts.
The XLogP3-AA value for JNJ-26481585 is 1.3.
The CAS number for JNJ-26481585 is 875320-29-9.