Structure

Jnj-26481585

CAS
875320-29-9
Catalog Number
ACM875320299
Category
Other Products
Molecular Weight
394.47014
Molecular Formula
C21H26N6O2

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Specification

Synonyms
JNJ-26481585;N1-(2-(1H-indol-3-yl)ethyl)-N4-(pyridin-4-yl)benzene-1,4-diaMine;N-Hydroxy-2-[4-[[[(1-methyl-1H-indol-3-yl)methyl]amino]methyl]-1-piperidinyl]-5-pyrimidinecarboxamide;Quisinostat;N-Hydroxy-2-(4-((((1-methyl-1H-indol-3-yl)methyl)amino)-methyl)piperidin-1-yl)pyrimidine-5-carbox;N-Hydroxy-2-(4-((((1-Methyl-1H-indol-3-yl)Methyl)aMino)Methyl)piperidin-1-yl)pyriMidine-5-carboxaMide;Quisinostat (JNJ-26481585);Quisinostat (JNJ-26481585) 2HCl
Density
1.35
What is the molecular formula of JNJ-26481585?

The molecular formula of JNJ-26481585 is C21H26N6O2.

When was JNJ-26481585 first created?

JNJ-26481585 was first created on October 26, 2006.

What is the molecular weight of JNJ-26481585?

The molecular weight of JNJ-26481585 is 394.5 g/mol.

What is another name for JNJ-26481585?

Another name for JNJ-26481585 is Quisinostat.

What is the potential antineoplastic activity of JNJ-26481585?

JNJ-26481585 is a second-generation, hydroxamic acid-based inhibitor of histone deacetylase (HDAC) with potential antineoplastic activity.

How does JNJ-26481585 inhibit HDAC?

JNJ-26481585 inhibits HDAC leading to an accumulation of highly acetylated histones, which may result in an induction of chromatin remodeling; inhibition of the transcription of tumor suppressor genes; inhibition of tumor cell division; and the induction of tumor cell apoptosis.

What is the InChIKey for JNJ-26481585?

The InChIKey for JNJ-26481585 is PAWIYAYFNXQGAP-UHFFFAOYSA-N.

How many hydrogen bond donor counts are in JNJ-26481585?

JNJ-26481585 has 3 hydrogen bond donor counts.

What is the XLogP3-AA value for JNJ-26481585?

The XLogP3-AA value for JNJ-26481585 is 1.3.

What is the CAS number for JNJ-26481585?

The CAS number for JNJ-26481585 is 875320-29-9.

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