Meptyldinocap

• CAS: 131-72-6
• Catalog Number: ACM131726
• Category: Main Products
• Molecular Weight: 364.39
• Molecular Formula: C18H24N2O6
• Synonyms: (E)-Crotonic Acid 2-(1-methylheptyl)-4,6-dinitrophenyl Ester; Meptyldinocap; Xiaobenjunzhi
• Appearance: Clear pale yellow oil

Case Study

Determination of Meptyldinocap Fungicide in Cucumber and Soil

Zhang, Zhiyong, et al Pest management science, 2014, 70(1), 97-102.

Meptyldinocap is a fortified product of the methylheptyl isomer of single dinitro-octylphenyl crotonate (2,4-DNOPC). It is a new powdery mildew fungicide with both protectant and post-infection activity. In this work, a method using LC-MS/MS was developed to determine 2,4-DNOPC in cucumber and soil. Its degradation pattern and residual level in cucumber and soil were also studied.
Evaluation methods and results
· In the LC-MS/MS determination, the mobile phase A consisted of a mixture of water and methanol along with 0.01 M ammonium formate and 0.1% formic acid, while mobile phase B comprised 0.1% formic acid in methanol. The ratio of mobile phase A to mobile phase B was 90:10 (v/v), and the flow rate was maintained at 0.4 mL min-1. The detection was conducted in electrospray positive ionization using multiple reaction monitoring (MRM) mode. Meptyldinocap's retention time under optimized conditions was approximately 2.7 min
· The recovery rates of meptyldinocap from cucumber and soil samples ranged from 81.4% to 95.1%. The quantification limits were determined to be 0.01 mg kg-1 for both cucumber and soil. The half-lives of meptyldinocap were observed to range between 1.6 and 2.2 days in cucumbers and between 3.1 and 4.4 days in soils. Residue levels of meptyldinocap in cucumbers were between less than 0.01 mg kg-1 and 0.92 mg kg-1, while in soils, they ranged from below 0.01 mg kg-1 to 0.53 mg kg-1. Five days after application, the residue levels of meptyldinocap in cucumbers across all treatments were below 0.1 mg kg-1.

Evaluation of the Biological Efficacy of Meptyldinocap Against Chilli Powdery Mildew

Jain, Y. K., et al. Indian Journal of Horticulture, 2010, 67(4), 292-294.

The biological efficacy of 35% meptyldinocap 35% EC (DE-126) against chilli powdery mildew (Leveillula taurica (Lev.) Arn.) was evaluated and compared with other fungicides.
Experimental design and evaluation results
· The experiment was designed using a randomized block format with three replications. The crop was planted with a spacing of 60×45 cm (row by plant) and all recommended agronomic practices were implemented to ensure healthy growth. The treatments tested included meptyldinocap 35% EC (DE-126) applied at rates of 90, 108, and 120 g a.i./ha, triadimefon 25% WP at 38 g a.i./ha, dinocap 48% EC at 108 g a.i./ha, sulphur 80% WP at 2500 g a.i./ha, and an untreated control. Each treatment received three sprays at 20-day intervals, beginning with the onset of disease symptoms, utilizing a knapsack sprayer with a spray volume of 600 liters per hectare. The significant differences among treatments were assessed through analysis of variance (ANOVA) and least significant difference (LSD) calculations.
· The results indicate that meptyldinocap 35% EC (DE-126) at 120 g a.i./ha was notably effective in managing powdery mildew, showing the lowest disease intensities of 8.52% in 2006-07 and 8.87% in 2007-08. Similarly, meptyldinocap 35% EC (DE-126) at 108 g a.i./ha also performed well, with disease intensities of 10.37% in 2006-07 and 13.33% in 2007-08, demonstrating comparable efficacy.

Meptyldinocap applications reduce inoculum in grapevine powdery mildew

Redl, Markus, et al. Crop Protection 149 (2021): 105760.

Strategies to control powdery mildew in grapevine need to consider the development of fungicide resistance. The effects of low resistance risk fungicides (copper oxychloride, potassium bicarbonate, meptyldinocap, wettable sulphur) on inoculum reduction were studied in the laboratory and as separate postharvest and bud break treatments. Ascospore viability and shedding were analyzed after postharvest treatments, and disease incidence and severity in grapevines were determined after bud break treatments. In the laboratory, all fungicides reduced ascospore viability, although the decrease was more pronounced in spring than in fall. Postharvest field applications of copper oxychloride, potassium bicarbonate, meptyldinocap, and wettable sulphur in fall 2017 significantly reduced (p < 0.001) the percentage of viable chasmothecia by 56-74%. In fall 2018, the fungicides tested had no effect on the percentage of viable chasmothecia. In Andau, the percentage of viable chasmothecia was only reduced by copper oxychloride (p = 0.029). The number of viable ascospores was significantly reduced by 46-70% after postharvest field treatments with fungicides, while for mesothelioma only a trend could be determined. The data indicate the importance of using fungicides during the pre-flowering phase for effective control, as the time from initial infection to flowering is long. In addition, this study shows that post-harvest spraying with low-risk fungicides at the end of the season spraying program can help reduce the number of fungicide treatments required for powdery mildew control.
In 2018 and 2019, the effects of four fungicides copper oxychloride, potassium bicarbonate, meptyldinocap, wettable sulphur on ascospore viability and schizospore release were studied. All fungicides, except mesothelioma, were multisite inhibitors with low to zero resistance risk. Therefore, the filter paper discs with chasmothecia were sprayed with distilled water (control) or fungicides (4 replicates each) using only the spray tower. To obtain excellent spray coverage, the spray volume was adjusted to 2.4 μl/cm. After each fungicide, the spray tower was carefully cleaned twice with distilled water, once with acetone and finally 3 times with distilled water. The filter paper discs were dried at room temperature and then placed in petri dishes. These petri dishes were sealed and incubated at 22°C in the dark for 14 days.

Effects of meptyldinocap on Typhlodromus pyri in European vineyards

Brunelli, Agostino, et al. ATTI Giornate Fitopatologiche 2010. Vol. 2. CLUEB, 2010. 419-426.

The effects of the fungicides mancozeb, myclobutanil, and meptyldinocap on populations of Typhlodromus pyri Scheuten were evaluated under field conditions and applied following recommended good agricultural practices. Population reductions compared to the control were analyzed using two complementary statistical models: linear mixed models were used to estimate the mean effect of the fungicides and generalized linear mixed models were used to estimate the cumulative probability that these effects were equal to or less than a specific IOBC category. Results from 27 field trials conducted in different grape-growing regions showed that the use of mancozeb, myclobutanil, and meptyldinocap had minimal effects on naturally occurring populations of T. pyri. Both statistical models confirmed that, although adverse effects on T. pyri could occur under certain conditions after repeated applications of any of the three fungicides studied, the probability of their occurrence was low and they were not persistent.
A series of 27 field studies were conducted in vineyards to investigate the effects of the fungicides mancozeb, myclobutanil, and meptyldinocap on the predatory mite T. pyri. The studies were conducted over different seasons in vineyards in central and southern Europe, reflecting a range of different environmental and agronomic conditions. The trial sites were placed in vineyards that had previously been treated with myclobutanil and meptyldinocap an average of 0.5-1 times per season, while mancozeb was used more frequently per season because it is present in several commonly used downy mildew products.

Custom Q&A

What is the molecular formula of Meptyldinocap?

The molecular formula of Meptyldinocap is C18H24N2O6.

What is the molecular weight of Meptyldinocap?

The molecular weight of Meptyldinocap is 364.4 g/mol.

Is Meptyldinocap soluble in water?

No, Meptyldinocap is nearly insoluble in water.

What is the chemical classification of Meptyldinocap?

Meptyldinocap is classified as a fungicide and acaricide.

What are the synonyms for Meptyldinocap?

The synonyms for Meptyldinocap include Meptyldinocap [ISO], 2,4-DNOPC, and OQU8KLU91P.

What is the IUPAC name of Meptyldinocap?

The IUPAC name of Meptyldinocap is (2,4-dinitro-6-octan-2-ylphenyl) (E)-but-2-enoate.

Can you provide the InChI of Meptyldinocap?

The InChI of Meptyldinocap is InChI=1S/C18H24N2O6/c1-4-6-7-8-10-13(3)15-11-14(19(22)23)12-16(20(24)25)18(15)26-17(21)9-5-2/h5,9,11-13H,4,6-8,10H2,1-3H3/b9-5+.

What are the CAS numbers associated with Meptyldinocap?

The CAS numbers associated with Meptyldinocap are 131-72-6 and 39300-45-3.

Is Meptyldinocap listed in any chemical databases?

Yes, Meptyldinocap is listed in various chemical databases such as CAMEO Chemicals, European Chemicals Agency (ECHA), Hazardous Substances Data Bank (HSDB), and ILO-WHO International Chemical Safety Cards (ICSCs).

Are there any other identifiers or codes for Meptyldinocap?

Yes, Meptyldinocap has other identifiers and codes such as UNII (OQU8KLU91P), DSSTox Substance ID (DTXSID90274056), and Wikidata (Q19296230).